Feasibility study of 2D Dixon-Magnetic Resonance Fingerprinting (MRF) of breast cancer

Zanderigo, Eloisa; Huck, Luisa; Distelmaier, Martina; Dethlefsen, Ebba; Maywald, Mirjam; Truhn, Daniel; Dirrichs, Timm; Doneva, Mariya; Schulz, Volkmar; Kühl, Christiane; Nolte, Teresa

doi:10.1016/j.ejro.2022.100453

Cited by 1 publication

(2 citation statements)

References 37 publications

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“…It was found that this 2D MRF-Dixon technique produces clearer maps that show delineation between fibroglandular and fatty tissue and improved accuracy of T1 and T2 measurements. Zanderigo et al 135 performed validation of this technique in a prospective study on 14 patients with both precontrast and postcontrast MRF maps. They found that using MRF-Dixon, T1 and T2 values of breast cancer were significantly higher than fibroglandular tissue on precontrast maps (T1: P = 0.007; T2: P = 0.03).…”

Section: Current Clinical Applicationsmentioning

confidence: 99%

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Magnetic Resonance Fingerprinting

et al. 2023

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Magnetic Resonance (MR) is an exceptionally powerful and versatile measurement technique. The basic structure of an MR experiment has remained nearly constant for almost 50 years. Here we introduce a novel paradigm, Magnetic Resonance Fingerprinting (MRF) that permits the noninvasive quantification of multiple important properties of a material or tissue simultaneously through a new approach to data acquisition, post-processing and visualization. MRF provides a new mechanism to quantitatively detect and analyze complex changes that can represent physical alterations of a substance or early indicators of disease. MRF can also be used to specifically identify the presence of a target material or tissue, which will increase the sensitivity, specificity, and speed of an MR study, and potentially lead to new diagnostic testing methodologies. When paired with an appropriate pattern recognition algorithm, MRF inherently suppresses measurement errors and thus can improve accuracy compared to previous approaches.

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Section: Current Clinical Applicationsmentioning

confidence: 99%

“…Overall, the precontrast findings were similar to those obtained by Chen et al 133 and suggest potential use of MRF to supplement precontrast differentiation of breast tissue. 133,135 This remains to be validated on a larger scale.…”

Section: Breast Imagingmentioning

confidence: 99%