Feasibility study for evaluating early lumbar facet joint degeneration using axial T1ρ, T2, and mapping in cartilage

Hu, Jianzhong; Zhang, Yi; Duan, Chunyue; Peng, Xuebiao; Hu, Ping; Lü, Hongbin

doi:10.1002/jmri.25596

Cited by 9 publications

(10 citation statements)

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“…T2 mapping is one of useful modalities for clinical quantitative imaging of articular cartilage and IVD [1,12]. It allows quantification of water content and collagen orientation by measuring T2 values, and can be used to detect degeneration of tissue in cartilage and IVDs occurring in the early stage [8,9].…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Low back pain (LBP) is one of the most frequent symptoms [1,2], and so there are a lot of opportunities to examine patients with LBP in clinic. The number of patients suffering from LBP is very high all over the world, and so LBP is a serious problem affecting medical economy [1,3]. According to the data from comprehensive survey of living conditions, 2013 in Japan, which has been performed by Ministry of Health, Labor and Welfare in our country, the complaining ratio of the LBP was approximately 9.2% in male (92.2 per 1000 people), and 11.8% in female (118.2 per 1000 people) [4].…”

Section: Introductionmentioning

confidence: 99%

“…In recent years, improvement of MRI led to the development of quantitative imaging techniques [8e11]. T2 mapping is one of useful method of MRI for clinical quantitative imaging of articular cartilage [1,12,13]. Most of the previous reports on T2 mapping in limb joints studied large joints such as knees [10,11,14,15].…”

Section: Introductionmentioning

confidence: 99%

“…Assessment of T2 values of degenerated IVDs and relevance of LBP to T2 values of IVDs were reported in several peerreviewed literature [5,6]. But, there are few reports on the research of FJ using T2 mapping [1,12,13]. Furthermore, as far as we know, there is no report that T2 values of FJ in subjects without lumbar spinal disorders, who were divided into age groups, were investigated using T2 mapping.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of age-related changes in lumbar facet joints using T2 mapping

Enokida

Tanishima

Tanida

et al. 2020

Journal of Orthopaedic Science

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Background: The purpose in this study is to investigate the T2 value of lumbar facet joint (FJ) in subjects without lumbar spinal disorders, age from 20s to 70s, using T2 mapping, and to evaluate the correlation between age and T2 value. And also, we investigated the T2 value of lumbar intervertebral disc (IVD) in the same way as FJ, and evaluated the correlation between the T2 value of FJ and that of IVD. Methods: We investigated 60 volunteers (30 male, 30 female), who were recruited from six age groups, 20se70s (10 subjects in each decade; 5 male, 5 female). We measured the T2 values of FJ at the L4/5 level in axial image and those of IVD (nucleus pulposus; NP, anterior and posterior annulus fibrosus; AAF and PAF) at the L4/5 level in midline sagittal image. We investigated the correlation between age and T2 value of FJ, and the correlation between the T2 value of FJ and that of IVD. Results: There was a strong positive correlation between age and T2 value of FJ (r ¼ 0.717). Age and T2 values of IVD were negatively correlated (NP; r ¼ À0.728, AAF; r ¼ À0.696, PAF; r ¼ À0.580). There was a negative correlation between T2 value of FJ and that of IVD (NP; r ¼ À0.575, AAF; r ¼ À0.617, PAF; r ¼ À0.492). Conclusions: T2 value of FJ was significantly increased as age rose. Our results suggest that T2 mapping could detect the degenerative changes of FJ related to aging even in subjects without lumbar spinal disorders. The results of this study will be the reference data of FJ T2 value in order to evaluate the relationship between low back pain and FJ using T2 mapping.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Evaluation of age-related changes in lumbar facet joints using T2 mapping

Enokida

Tanishima

Tanida

et al. 2020

Journal of Orthopaedic Science

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Ultrafast T₂ and T₂* mapping using single‐shot spatiotemporally encoded MRI with reduced field of view and spiral out‐in‐out‐in trajectory

Jin,

Zhou,

Chen

et al. 2024

Medical Physics

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BackgroundT2 and T2* mapping are crucial components of quantitative magnetic resonance imaging, offering valuable insights into tissue characteristics and pathology. Single‐shot methods can achieve ultrafast T2 or T2* mapping by acquiring multiple readout echo trains. However, the extended echo trains pose challenges, such as compromised image quality and diminished quantification accuracy.PurposeIn this study, we develop a single‐shot method for ultrafast T2 and T2* mapping with reduced echo train length.MethodsThe proposed method is based on ultrafast single‐shot spatiotemporally encoded (SPEN) MRI combined with reduced field of view (FOV) and spiral out‐in‐out‐in (OIOI) trajectory. Specifically, a biaxial SPEN excitation scheme was employed to excite the spin signal into the spatiotemporal encoding domain. The OIOI trajectory with high acquisition efficiency was employed to acquire signals within targeted reduced FOV. Through non‐Cartesian super‐resolved (SR) reconstruction, 12 aliasing‐free images with different echo times were obtained within 150 ms. These images were subsequently fitted to generate T2 or T2* mapping simultaneously using a derived model.ResultsAccurate and co‐registered T2 and T2* maps were generated, closely resembling the reference maps. Numerical simulations demonstrated substantial consistency (R2 > 0.99) with the ground truth values. A mean difference of 0.6% and 1.7% was observed in T2 and T2*, respectively, in in vivo rat brain experiments compared to the reference. Moreover, the proposed method successfully obtained T2 and T2* mappings of rat kidney in free‐breathing mode, demonstrating its superiority over multishot methods lacking respiratory navigation.ConclusionsThe results suggest that the proposed method can achieve ultrafast and accurate T2 and T2* mapping, potentially facilitating the application of T2 and T2* mapping in scenarios requiring high temporal resolution.

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Automated cartilage segmentation and quantification using 3D ultrashort echo time (UTE) cones MR imaging with deep convolutional neural networks

et al. 2021

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Feasibility study for evaluating early lumbar facet joint degeneration using axial T₁ρ, T₂, and mapping in cartilage

Abstract: 1 Technical Efficacy: Stage 2 J. MAGN. RESON. IMAGING 2017;46:468-475.

Cited by 9 publications

References 40 publications

Evaluation of age-related changes in lumbar facet joints using T2 mapping

Evaluation of age-related changes in lumbar facet joints using T2 mapping

Ultrafast T₂ and T₂* mapping using single‐shot spatiotemporally encoded MRI with reduced field of view and spiral out‐in‐out‐in trajectory

Automated cartilage segmentation and quantification using 3D ultrashort echo time (UTE) cones MR imaging with deep convolutional neural networks

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Feasibility study for evaluating early lumbar facet joint degeneration using axial T1ρ, T2, and mapping in cartilage

Abstract: 1 Technical Efficacy: Stage 2 J. MAGN. RESON. IMAGING 2017;46:468-475.

Cited by 9 publications

References 40 publications

Evaluation of age-related changes in lumbar facet joints using T2 mapping

Evaluation of age-related changes in lumbar facet joints using T2 mapping

Ultrafast T2 and T2* mapping using single‐shot spatiotemporally encoded MRI with reduced field of view and spiral out‐in‐out‐in trajectory

Automated cartilage segmentation and quantification using 3D ultrashort echo time (UTE) cones MR imaging with deep convolutional neural networks

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Product

Resources

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Feasibility study for evaluating early lumbar facet joint degeneration using axial T₁ρ, T₂, and mapping in cartilage

Ultrafast T₂ and T₂* mapping using single‐shot spatiotemporally encoded MRI with reduced field of view and spiral out‐in‐out‐in trajectory