Feasibility, Procedural Morbidity and Mortality, and Long-Term Follow-Up of Endovascular Treatment of 321 Unruptured Aneurysms

Abstract

BACKGROUND AND PURPOSE:The purpose of our study was to evaluate the technical feasibility, morbidity and mortality, and durability of occlusion of unruptured aneurysms treated with Guglielmi detachable coils (GDCs) with a long-term follow-up.

Endovascular Therapy of 500 Small Asymptomatic Unruptured Intracranial Aneurysms

“…10,[19][20][21][22] In our series, failure occurred in 3.8% (19/500), which is lower compared with that in previous reports. An unfavorable D/N ratio of Ͻ1.5 is considered the most responsible factor.…”

“…The patient was lost to clinical follow-up after initial treatment. Gallas et al 19 did not experience posttreatment aneurysmal SAH in the 278 UIAs making up 77% of the aneurysms of Ͻ10 mm endovascularly treated, with a mean follow-up period of 38 months. In our series, there were no patients who had aneurysmal SAH after endovascular therapy, with a mean follow-up of 34.7 months.…”

Long-Term Follow-Up of 1036 Cerebral Aneurysms Treated by Bare Coils: A Multicentric Cohort Treated between 1998 and 2003

“…Initial feasibility and acute outcome results for ruptured and unruptured aneurysms in this series have been published. 10,13,14 All patients treated with an endovascular technique were sought and included those with berry aneurysms and large and giant aneurysms. Only dissecting vertebral aneurysms were excluded from this multicentric study because it is known that the evolution of these aneurysms differs from that of saccular aneurysms.…”

“…Feasibility, morbidity-mortality, and initial results were previously published. 13,14 We present the long-term results of occlusion after follow-up (mean, 66 months; range, 3-10 years).…”

“…3 Some articles have been published pertaining to the stability of occlusions treated with detachable coils and the efficacy of providing protection against growth or regrowth of the aneurysm and consequent bleeding. [4][5][6][7][8][9][10][11][12][13][14][15][16] Long-term follow-up and the rate of recanalization due to coil compaction, typically caused by unfavorable morphologic characteristics such as lesion and neck size, remain a disadvantage compared with surgical treatment.…”