Feasibility of Using a Real-time 3-Dimensional Technique for Contrast Dobutamine Stress Echocardiography

Pulerwitz, Todd; Hirata, Kumiko; Abe, Yukio; Otsuka, Ryo; Herz, Susan L.; Okajima, Kazue; Jin, Zhezhen; Tullio, Marco R. Di; Homma, Shunichi

doi:10.1016/j.echo.2005.12.006

Cited by 61 publications

(40 citation statements)

References 14 publications

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“…We found that with the use of selective dual triggering to minimize bubble destruction by ultrasound energy, contrast enhancement increased the accuracy of RT3DE-based analysis of regional LV function against CMR reference and its reproducibility to levels similar to those noted in patients with optimal image quality. 33 Several other studies that used contrast enhancement with dobutamine stress have demonstrated that it improved segmental endocardial visualization 34 and resulted in high levels of agreement with 2DE-based wall motion scores. 35 Although the results of these studies may have important implications on the use of contrast for volumetric quantification of both global and regional LV function, no studies published to date have demonstrated the ability of contrast enhancement to improve the diagnostic accuracy of stress testing.…”

Section: Contrast-enhanced Rt3de Imagingmentioning

confidence: 99%

Real-Time 3-Dimensional Echocardiography

2009

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O ne of the most significant developments of the last decade in ultrasound imaging of the heart was the evolution of 3-dimensional (3D) imaging from slow and labor-intense offline reconstruction to real-time volumetric imaging. This imaging modality provides valuable clinical information that empowers echocardiographers with new levels of confidence in the diagnosis of heart disease. We have previously described the technological milestones in the development of real-time 3D echocardiographic (RT3DE) imaging and its major advantages over conventional 2-dimensional echocardiography (2DE) and reviewed the published literature that supported the use of this new methodology in clinical practice. 1 Since 2006, the growing availability of RT3DE technology, its ease of use, and its multiple attractive features have sparked significant interest in the research community, resulting in a large number of publications, most of which have endorsed RT3DE imaging for clinical use by demonstrating its unique capabilities in different scenarios. In parallel, the clinical acceptance of this new tool has broadened significantly. The most recent clinically significant addition is matrix-array transesophageal echocardiography (TEE), which provides images of unprecedented quality that aid surgeons and interventional cardiologists in planning and guiding procedures and evaluating their outcomes.The purpose of the present article is to review the most recent RT3DE literature and provide readers with an update on the latest developments and the current status of this noninvasive imaging tool. Because different potential applications of RT3DE imaging have been explored to various extents, they are described here separately, and each is discussed with an emphasis on the scientifically established facts, along with the known stumbling blocks and difficulties. Quantification of LV Volumes and FunctionA firmly established advantage of 3D imaging over crosssectional slices of the heart is the improvement in the accuracy of the evaluation of left ventricular (LV) volumes and ejection fraction (EF) by eliminating the need for geometric modeling, which is inaccurate in the presence of aneurysms, asymmetrical ventricles, or wall motion abnormalities, and the errors caused by foreshortened views even in symmetrical ventricles. The value of RT3DE imaging in this context has been demonstrated by multiple studies that compared RT3DE volume measurements with widely accepted reference techniques, including radionuclide ventriculography and cardiac magnetic resonance (CMR). [2][3][4][5][6] These studies and others have demonstrated higher levels of agreement between the RT3DE approach and the respective reference technique compared with conventional 2DE methodology. Additionally, RT3DE measurements were found to be more reproducible than 2DE 4,5,7 and, in some studies, even as reproducible as CMR. 8 Interestingly, in a recent study in patients after myocardial infarction (MI), 9 RT3DE-derived LV volumes were more accurate and more reproducible than thos...

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Section: Contrast-enhanced Rt3de Imagingmentioning

confidence: 99%

Real-Time 3-Dimensional Echocardiography

2009

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“…The feasibility of real time 3DE and its good concordance with 2D echo on wall motion analysis for detection of inducible ischemia has been reported in several studies (Table 3) [19][20][21][22][23][24][25]. With the exception of few authors [24], reported sensitivity rates are high.…”

Section: Assessment or Regional Wall-motion Abnormalitiesmentioning

confidence: 83%

Real-time three-dimensional echocardiography: never before clinical efficacy looked so picturesque

Aggeli

Felekos

Kastellanos

et al. 2015

International Journal of Cardiology

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“…Both physical stress (either bicycle or treadmill exercise) and pharmacological stress (mainly dobutamine plus atropine, rarely dipyridamole) have been used in combination with 3D techniques. Several studies described the additional use of left heart contrast agents for better endocardial delineation [6] [7].…”

Section: Methodsmentioning

confidence: 99%

Three-dimensional stress echocardiography

Franke¹

2015

Three-Dimensional Echocardiography

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Feasibility of Using a Real-time 3-Dimensional Technique for Contrast Dobutamine Stress Echocardiography

Cited by 61 publications

References 14 publications

Real-Time 3-Dimensional Echocardiography

Real-Time 3-Dimensional Echocardiography

Real-time three-dimensional echocardiography: never before clinical efficacy looked so picturesque

Three-dimensional stress echocardiography

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