Feasibility of Transcranial Motor Evoked Potentials and Electromyography during MRI-Guided Laser Interstitial Thermal Therapy for Glioblastoma

Sharma, Mayur; Scott, Victoria A; Ball, Tyler; Castle, Joshua R; Williams, Brian J.

doi:10.1016/j.wneu.2022.12.135

Cited by 2 publications

(1 citation statement)

References 18 publications

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“…Sharma et al [ 19 ] describe another approach to asleep LITT in eloquent areas. Their technique for LITT-ablation of a left thalamic GBM employed intraoperative transcranial motor evoked potentials (MEP), somatosensory evoked potentials (SSEP), and free-running electromyography (EMG) in a patient with preoperative right-sided weakness.…”

Section: Discussionmentioning

confidence: 99%

Functional magnetic resonance imaging (fMRI) as adjunct for planning laser interstitial thermal therapy (LITT) near eloquent structures

Rifi,

Harary,

Walshaw

et al. 2024

Acta Neurochir

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LITT is a minimally-invasive laser ablation technique used to treat a wide variety of intracranial lesions. Difficulties performing intraoperative mapping have limited its adoption for lesions in/near eloquent regions. In this institutional case series, we demonstrate the utility of fMRI-adjunct planning for LITT near language or motor areas. Six out of 7 patients proceeded with LITT after fMRI-based tractography determined adequate safety margins for ablation. All underwent successful ablation without new or worsening postoperative symptoms requiring adjuvant corticosteroids, including those with preexisting deficits. fMRI is an easily accessible adjunct which may potentially reduce chances of complications in LITT near eloquent structures.

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Section: Discussionmentioning

confidence: 99%