Feasibility of spectral imaging with low-concentration contrast medium in abdominal CT angiography of obese patients

Liu, Yijun; Liu, Ailian; Лю, Лэй; Song, Tian; Liu, Jinghong; Pu, Renwang; Fang, Xin; Liu, Xiaofeng; Yuan, Gang

doi:10.1111/ijcp.12856

Cited by 11 publications

(8 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The low-dose MR group had higher CT attenuation than the normal-dose MR group, as lowering tube voltage can significantly increase CT attenuation. When reducing the tube voltage, the IN can be increased, and the SNR or CNR can be reduced (18). However, our study showed that the IN of the low-dose MR group was lower than that of (21).…”

Section: Perioperative Resultsmentioning

confidence: 53%

Mixed reality models based on low-dose computed tomography technology in nephron-sparing surgery are better than models based on normal-dose computed tomography

Guan¹,

Cao²,

Jinbao³

et al. 2021

Quant Imaging Med Surg

View full text Add to dashboard Cite

Background: Nephron-sparing surgery has been widely applied in the treatment of renal tumors. Previous studies have confirmed the advantages of mixed reality technology in surgery. The study aimed to explore the optimization of mixed reality technology and its application value in nephron-sparing surgery.Methods: In this prospective study of 150 patients with complex renal tumors (RENAL nephrometry score ≥7) who underwent nephron-sparing surgery, patients were randomly divided into Group A (the normal-dose mixed reality group, n=50), Group B (the low-dose mixed reality group, n=50), and Group C (the traditional computed tomography image group, n=50). Group A and Group C received the normaldose computed tomography scan protocol: 120 kVp, 400 mA, and 350 mgI/mL, while Group B received the low-dose computed tomography scan protocol: 80 kVp, automatic tube current modulation, and 320 mgI/mL. All computed tomography data were transmitted to a three-dimensional visualization workstation and underwent modeling and mixed reality imaging. Two senior surgeons evaluated mixed reality quality. Objective indexes and perioperative indexes were calculated and compared.Results: Compared with Group A, the radiation effective dose in Group B was decreased by 39.6%.The subjective scores of mixed reality quality in Group B were significantly higher than those of Group A (Z=−4.186, P<0.001). The inter-observer agreement between the two senior surgeons in mixed reality quality was excellent (K=0.840, P<0.001). The perioperative indexes showed that the mixed reality groups were significantly different from the computed tomography image group (all P<0.017). More cases underwent nephron-sparing surgery in the mixed reality groups than in the computed tomography image group (P<0.0017).Conclusions: Low-dose computed tomography technology can be effectively applied to mixed reality optimization, reducing the effective dose and improving mixed reality quality. Optimized mixed reality can significantly increase the cases of successful nephron-sparing surgery and improve perioperative indexes.

show abstract

Section: Perioperative Resultsmentioning

confidence: 53%

Mixed reality models based on low-dose computed tomography technology in nephron-sparing surgery are better than models based on normal-dose computed tomography

Guan¹,

Cao²,

Jinbao³

et al. 2021

Quant Imaging Med Surg

View full text Add to dashboard Cite

show abstract

“…The square of tube voltage is approximately inversely proportional to the radiation dose, and lower tube voltage could reduce the radiation dose more effectively, which has been demonstrated that it could been successfully used in imaging techniques such as CTA. [23][24][25] Some studies showed that kVp may be selected based on body size (body mass index, body width on scout topogram, or patient weight), 26 for example, 100 kVp can be used for patients weighing less than 150 lbs. In our study, the mean weight was 67.68 ± 1.43 (SD) kg (150lbs = 68.0388555 kg).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of BMI‐based tube voltage selection in CT colonography: A prospective comparison of low kV versus routine 120 kV protocol

Wang

Fan

et al. 2023

J Applied Clin Med Phys

Self Cite

View full text Add to dashboard Cite

To explore the value of individualized kVp selection based on the patient's body mass index (BMI, kg/m 2 ) in CT colonography (CTC). Materials and Methods: Seventy-eight patients underwent two CTC scans: conventional 120 kVp in supine position (Group A) with 30% Adaptive statistical iteration algorithm (ASIR-V) and BMI-based lower kV p in prone position (Group B): tube voltage was suggested by an experienced investigator according to the patient's body mass index (BMI; calculated as weight divided by height squared; kg/m (2)).70 kV for BMI < 23 kg/m 2 (Group B1, n = 27), 80 kV for 23 ≤ BMI ≤ 25 kg/m 2 (Group B2, n = 21) and 100 kV for BMI > 25 kg/m 2 (Group B3, n = 30). Group A, corresponding to the BMI value in Group B, was divided into A1, A2, and A3 subgroups for analysis. Groups B used ASIR-V of different weights (30%-90% ASIR-V). The Hounsfield Unit (HU) and SD values of the muscles and the intestinal cavity air were measured, and the signal-to-noise ratio (SNR) and the contrast-to-noise ratio (CNR) of images were calculated. Imaging quality was evaluated by two reviewers and statistically compared. Results:The 120 kV scans were preferred more than 50% of the time. All images had excellent quality with good consistency between reviewers (Kappa > 0.75, p < 0.05). The radiation dose was reduced in groups B1, B2 and B3 by 63.62%, 44.63%, and 32.14%, respectively, compared with group A (p < 0.05). The SNR and CNR values between group A1/A2/A3 and B1/B2/B3 + 60%ASIR-V were not statistically significant (p < 0.05). There was no statistically significant difference between the subjective scores of group B combined with 60%ASIR-V and group A (p > 0.05). Conclusion: BMI-based individualized kV CTC imaging significantly reduces overall radiation dose while providing an equal image quality with the conventional 120 kV. K E Y W O R D S colon, computed tomography INTRODUCTIONColorectal cancer (CRC) is one of the most common and deadly malignant tumor types. Its incidence is ris-This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

show abstract

“…15 Dual-energy CT is another approach to reduce the amount of contrast medium, while maintaining the image quality. 4,16 As much as 70% reduction in iodine dose with a total amount of 15 g iodine could be achieved using dual-energy CT. 4 One major strength of this technique is that the appropriate monochromatic image could be reconstructed out of multiple energy levels. 16 Another strength is that metal artifacts from stents might be reduced using monochromatic images.…”

Section: Discussionmentioning

confidence: 99%

“…4,16 As much as 70% reduction in iodine dose with a total amount of 15 g iodine could be achieved using dual-energy CT. 4 One major strength of this technique is that the appropriate monochromatic image could be reconstructed out of multiple energy levels. 16 Another strength is that metal artifacts from stents might be reduced using monochromatic images. 17 Combination of dual-energy CT and DRTB method might further reduce the amount of contrast medium necessary for CT of the aorta.…”

Section: Discussionmentioning

confidence: 99%

Double region of interest timing bolus technique following endovascular aortic repair: Short-term prognosis analysis

et al. 2019

View full text Add to dashboard Cite

Objectives To compare the incidence rate of reintervention in patients with and without complication findings at aortic computed tomography using double region of interest timing bolus (DRTB) method after endovascular stent placement of the aorta. Methods We included 40 patients who underwent computed tomography of the aorta using DRTB method after endovascular stent placement. DRTB method allows to scan the aorta with a short injection time of 9 s by synchronizing the scan speed to the aortic flow. Complication findings at computed tomography were defined as endoleak, rupture, occlusion, and infection. The primary endpoint was reintervention, which was defined as any of the following three events: conversion to open repair, graft revision, or secondary intervention. Results The mean contrast medium during computed tomography angiography was 38.6 ± 3.9 mL. Complication findings at computed tomography were present in 10 patients (25%): endoleak ( n = 9) and infection ( n = 1). During a median follow-up of 7 months (interquartile range, 4–11 months), two patients experienced reintervention. Kaplan–Meier curves by complication findings showed that event rate at 6 months was significantly higher in patients with complication findings than in patients without (20% vs 0%, p = 0.01). No patients without complication findings at computed tomography experienced reintervention. Conclusions No complication findings at computed tomography after intervention of the aorta resulted in good prognosis in patients who underwent aortic computed tomography using DRTB method.

show abstract

Feasibility of spectral imaging with low-concentration contrast medium in abdominal CT angiography of obese patients

Abstract: Compared with conventional CT, spectral CT imaging significantly reduces both radiation dose and contrast dose while maintaining image quality in abdominal CTA for patients with central obesity and high BMI.

Cited by 11 publications

References 17 publications

Mixed reality models based on low-dose computed tomography technology in nephron-sparing surgery are better than models based on normal-dose computed tomography

Mixed reality models based on low-dose computed tomography technology in nephron-sparing surgery are better than models based on normal-dose computed tomography

Evaluation of BMI‐based tube voltage selection in CT colonography: A prospective comparison of low kV versus routine 120 kV protocol

Double region of interest timing bolus technique following endovascular aortic repair: Short-term prognosis analysis

Contact Info

Product

Resources

About