Feasibility of semiautomated MR volumetry using gadoxetic acid–enhanced MRI at hepatobiliary phase for living liver donors

Abstract

Semiautomated liver MR volumetry using hepatobiliary phase gadoxetic acid-enhanced MRI with the quadratic MR image division is a reliable, easy, and fast tool to measure liver volume in potential living liver donors.

Histogram analyses of diffusion kurtosis indices and apparent diffusion coefficient in assessing liver regeneration after ALPPS and a comparative study with portal vein ligation

“…As proved by Lee et al, semiautomated liver MR volumetry using hepatobiliary‐phase gadoxetic acid‐enhanced MRI was a reliable and fast tool to measure liver volume, comparable to computed tomography (CT) volumetry. We used a computer‐aided semiautomatic liver volumetry software IQQA‐liver (v. 2.0; EDDA Technology, Princeton, NJ) running on the 20‐minute hepatobiliary phase T 1 ‐weighted volumetric interpolated breath‐hold examination sequence, with the following parameters: TR/TE = 4.43/1.53 msec, slice thickness = 2.0 mm, no interslice gap, field of view = 100 × 100 mm, following the administration of gadoxetic acid (0.1 ml/kg; Primovist; Bayer Healthcare, Berlin, Germany).…”

Liver volumetry: Is imaging reliable? Personal experience and review of the literature

“…Regarding liver transplantation, Ringe et al [36] emphasized the role of CT, reporting that this method of imaging of the liver, in combination with dedicated software, plays a key role in the evaluation of candidates for liver donor transplantation: based on the results of liver CT volumetry, 31% of the candidates of this series were excluded as donors. Lee et al [37] reported the usefulness of semi automated liver MR volumetry using hepatobiliary phase gadoxetic acid-enhanced images with the quadratic MR image division to measure liver volume in potential living liver donors; the average volume measurement error of the semi automated MR volumetry was 2.35% ± 1.22%. Zappa et al [38] applied CT volumetry to the evaluation of total and segmental liver regeneration after hepatectomy: CT was able to identify even segmental regeneration, reporting a 64% increase in liver volume from the future remnant 7 d after hepatectomy.…”

Fast and accurate liver volumetry prior to hepatectomy

“…4,6 With specialised software, auto-segmentation of organs is possible. [8][9][10][11][12][13][14] However, CT-based automated segmentation of the liver is challenging because organs with comparable density surround the liver. Automated future remnant liver volumetric analysis has not yet been validated by comparing it with manual slice-by-slice drawing of contours.…”