Feasibility of Monte-Carlo algorithm in comparison with collapse-cone dose calculation algorithm of a commercial treatment planning system in the presence of high-density metallic implant: a dosimetric study
Abstract:Background
The number of people with implanted hip prosthesis has grown worldwide. For radiotherapy planning of patients with hip implants, few main challenges are encountered. The aim of the present study was to evaluate the feasibility of different planning algorithms in the presence of high-density metallic implant in the treatment of patients with carcinoma cervix.
Results
It was found that D98% were 44.49 ± 0.11, 44.51 ± 0.13, 44.39 ± 0.22, an… Show more
“…This may be attributed to the differences in the dose-calculation models, the uncertainty of film dosimetry, and simplifications assumed by TPS-MC simulations in terms of physical processes [ 19 , 24 ]. Certain reports on dose calculations in TPSs have shown that they can be performed accurately, including around high-Z materials [ 25 , 26 ]. However, these reports were based on large-volume high-Z materials and not on extremely small high-Z materials, such as the seeds used in this study.…”
BackgroundThis study evaluates dose perturbations caused by nonradioactive seeds in clinical cases by employing treatment planning system-based Monte Carlo (TPS-MC) simulation.
MethodologyWe investigated dose perturbation using a water-equivalent phantom and 20 clinical cases of prostate cancer (10 cases with seeds and 10 cases without seeds) treated at
“…This may be attributed to the differences in the dose-calculation models, the uncertainty of film dosimetry, and simplifications assumed by TPS-MC simulations in terms of physical processes [ 19 , 24 ]. Certain reports on dose calculations in TPSs have shown that they can be performed accurately, including around high-Z materials [ 25 , 26 ]. However, these reports were based on large-volume high-Z materials and not on extremely small high-Z materials, such as the seeds used in this study.…”
BackgroundThis study evaluates dose perturbations caused by nonradioactive seeds in clinical cases by employing treatment planning system-based Monte Carlo (TPS-MC) simulation.
MethodologyWe investigated dose perturbation using a water-equivalent phantom and 20 clinical cases of prostate cancer (10 cases with seeds and 10 cases without seeds) treated at
“…The material used for was “titanium”(composition: titanium 88.5%–91.0%; aluminum 5.6%–6.5%, vanadium 3.5%–4.5%, iron 0.25%, oxygen 0.13% and carbon 0.08%, average ED 3.74 relative to water; diameter of femoral heads of prosthesis ranging from 40 to 54 mm. [ 20 ] The thermoplastic cast was made for every patient. The acquired images were transferred to Varian Soma vision contouring stations.…”
Purpose:
To study the impact of different optimization methods in dealing with metallic hip implant using intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT) techniques.
Materials and Methods:
A cohort of 16 patients having metallic implants was selected for the study. Three sets of IMRT and VMAT plans were generated. Set 1 IMRT (IM_Base), VMAT (VM_Base) without any restrictions on beam entry and exit, set 2 (IM_ENT and VM_ENT) optimizer restricts the beam entry and set 3 (IM_EXT+ENT), neither entry nor exit doses were allowed toward the metallic implant.
Results:
There was no significant difference in target (D
95%
) and organ-at-risk doses between IM_Base and IM_ENT. There were significant (
P
= 0.002) improvements in planning target volume (PTV) V
95%
and homogeneity from IM_EXT+ENT to IM_ENT. There was no significant difference in plan quality between VM_Base and VM_ENT. There were significant (
P
= 0.005) improvements in PTV, V
95%,
homogeneity from VM_EXT+ENT to VM_ENT. V
40Gy
, V
30Gy
for bladder, rectum, bowel, and bowel maximum dose decreases significantly (
P
< 0.005) in IM_ENT compared to IM_EXT+ENT, but not significant for VMAT plans. Similarly, there was a significant decrease in dose spill outside target (
P
< 0.05) comparing 40%, 50%, 60%, and 70% dose spills for IM_ENT compared to IM_EXT+ENT, but variations among VMAT plans are insignificant. VMAT plans were always superior to IMRT plans for the same optimization methods.
Conclusion:
The best approach is to plan hip prosthesis cases with blocked entry of radiation beam for IMRT and VMAT. The VMAT plans had more volumetric coverage, fewer hotspots, and lesser heterogeneity.
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