Feasibility of laparoscopic total proctocolectomy with ileal pouch–anal anastomosis and total colectomy with ileorectal anastomosis for familial adenomatous polyposis: results of a nationwide multicenter study

Konishi, Tsuyoshi; Ishida, Hideyuki; Ueno, Hideki; Kobayashi, Hirotoshi; Hinoi, Takao; Inoue, Yasuhiro; Ishida, Fumio; Kanemitsu, Yukihide; Yamaguchi, Tatsuro; Tomita, Naohiro; Matsubara, Nagahide; Watanabe, Toshiaki; Sugihara, Kenichi

doi:10.1007/s10147-016-0977-x

Cited by 34 publications

(34 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…All patients diagnosed as having FAP and undergoing colorectal resection in each institution between the years 2000 and 2012 were retrospectively collected and registered for the database as described previously 16, 17, 18. Patients having a previous history of colorectal resections were excluded from the database to avoid double registration.…”

Section: Methodsmentioning

confidence: 99%

“…These limitations could explain inconsistent results in the previous studies, and we need evidence that focuses on patients with FAP with the use of objective criteria for assessing complications. The aim of the present study was to compare postoperative complications and short‐term outcomes after stapled and hand‐sewn IPAA for patients with FAP using multicenter data in Japan 16, 17, 18…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Postoperative complications after stapled and hand‐sewn ileal pouch‐anal anastomosis for familial adenomatous polyposis: A multicenter study

Konishi

Ishida

Ueno

et al. 2017

Annals of Gastroent Surgery

Self Cite

View full text Add to dashboard Cite

Ileal pouch‐anal anastomosis (IPAA) after total proctocolectomy (TPC) can be conducted with either hand‐sewn or stapled anastomosis for patients with familial adenomatous polyposis (FAP). Although stapled IPAA without mucosectomy has a higher risk for developing adenomas in the remnant mucosa, it is the simpler procedure with potential benefit in short‐term outcomes. However, it remains controversial as to whether stapled IPAA has any advantages in reducing postoperative complications. The aim of the present study was to compare the postoperative complications and short‐term outcomes of stapled and hand‐sewn IPAA for patients with FAP, using a multicenter cohort sample in Japan. Data of 143 patients with FAP who underwent TPC with stapled IPAA (n=37) and hand‐sewn IPAA (n=106) at 23 institutions between 2000 and 2012 were collected. Postoperative complications, proportion of ostomy, fecal continence and overall survival were compared. Overall rates of the Clavien‐Dindo grade II‐IV complications were not different between the two groups (19% in stapled vs 25% in hand‐sewn, P=.42), with significantly fewer pouch‐related complications including leakage, pelvic abscess, vaginal fistula and anastomotic stricture in stapled IPAA (none in stapled vs 11% in hand‐sewn, P=.036). There was no mortality. Proportion of ostomy at 12 months was similar (2.7% in stapled vs 4.3% in hand‐sewn, P=.26). Mean Wexner score was similar. (0.47 in stapled vs 2.0 in hand‐sewn, P=.12). Five‐year overall survival excluding Stage IV patients was 96% in both groups. Stapled IPAA is a safe option in patients with FAP with a potential benefit in reducing pouch‐related complications.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Postoperative complications after stapled and hand‐sewn ileal pouch‐anal anastomosis for familial adenomatous polyposis: A multicenter study

Konishi

Ishida

Ueno

et al. 2017

Annals of Gastroent Surgery

Self Cite

View full text Add to dashboard Cite

show abstract

“…The JSCCR multicenter study showed that temporary ileostomy was performed in 55% of patients who had undergone IPAA 25) . A systematic review of the closure of temporary ileostomy 52) revealed that closure was safe, but that 16.5% of all subjects had postoperative complications, including bowel obstruction in 7.6% (reoperation in 2.9% of all cases), anastomotic leakage in 2.0%, wound infection in 4.0%, and late complications such as incisional hernia in 1.9% and bowel obstruction in 9.4%.…”

Section: Cq4: Is Temporary Ileostomy Required In Cases Undergoing Ipamentioning

confidence: 99%

“…(1) Total proctocolectomy + permanent ileostomy (TPC) (2) Restorative proctocolectomy + ileal pouch-anal anastomosis (IPAA) (3) Total colectomy + ileorectal anastomosis (IRA) At present, IPAA is thought to be the standard surgical procedure and it is commonly performed in FAP patients [22][23][24][25] . (CQ3,CQ4)…”

Section: S11mentioning

confidence: 99%

“…Hideyuki Ishida 1) , Tatsuro Yamaguchi 2) , Kohji Tanakaya 3) , Kiwamu Akagi 4) , Yasuhiro Inoue 5) , Kensuke Kumamoto 6) , Hideki Shimodaira 7) , Shigeki Sekine 8) , Toshiaki Tanaka 9) , Akiko Chino 10) , Naohiro Tomita 11) , Takeshi Nakajima 12) , Hirotoshi Hasegawa 13) , Takao Hinoi 14) , Akira Hirasawa 15) , Yasuyuki Miyakura 16) , Yoshie Murakami 17) , Kei Muro 18) , Yoichi Ajioka 19) , Yojiro Hashiguchi 20) , Yoshinori Ito 21) , Yutaka Saito 22) , Tetsuya Hamaguchi 23) , Megumi Ishiguro 24) , Soichiro Ishihara 9) , Yukihide Kanemitsu 25) , Hiroshi Kawano 26) , Yusuke Kinugasa 27) , Norihiro Kokudo 28) , Keiko Murofushi 29) , Takako Nakajima , Narikazu Boku 23) , Takahiro Fujimori 39) , Michio Itabashi 40) , Nobuo Koinuma 41) , Takayuki Morita 42) , Genichi Nishimura 43) , Yuh Sakata 44) , Yasuhiro Shimada 45) , Keiichi Takahashi 2) , Shinji Tanaka 46) , Osamu Tsuruta 47) , Toshiharu Yamaguchi 48)…”

unclassified

See 1 more Smart Citation

Japanese Society for Cancer of the Colon and Rectum (JSCCR) Guidelines 2016 for the Clinical Practice of Hereditary Colorectal Cancer (Translated Version)

Ishida

Yamaguchi

Tanakaya

et al. 2018

J Anus Rectum Colon

Self Cite

View full text Add to dashboard Cite

Hereditary colorectal cancer accounts for less than 5% of all colorectal cancer cases. Some of the unique characteristics that are commonly encountered in cases of hereditary colorectal cancer include early age at onset, synchronous/metachronous occurrence of the cancer, and association with multiple cancers in other organs, necessitating different management from sporadic colorectal cancer. While the diagnosis of familial adenomatous polyposis might be easy because usually 100 or more adenomas that develop in the colonic mucosa are in this condition, Lynch syndrome, which is the most commonly associated disease with hereditary colorectal cancer, is often missed in daily medical practice because of its relatively poorly defined clinical characteristics. In addition, the disease concept and diagnostic criteria for Lynch syndrome, which was once called hereditary non‐polyposis colorectal cancer, have changed over time with continual research, thereby possibly creating confusion in clinical practice. Under these circumstances, the JSCCR Guideline Committee has developed the “JSCCR Guidelines 2016 for the Clinical Practice of Hereditary Colorectal Cancer (HCRC)," to allow delivery of appropriate medical care in daily practice to patients with familial adenomatous polyposis, Lynch syndrome, or other related diseases. The JSCCR Guidelines 2016 for HCRC were prepared by consensus reached among members of the JSCCR Guideline Committee, based on a careful review of the evidence retrieved from literature searches, and considering the medical health insurance system and actual clinical practice settings in Japan. Herein, we present the English version of the JSCCR Guidelines 2016 for HCRC.

show abstract

Quality-of-life implications of risk-reducing cancer surgery

Altman

Hui

Tuttle

2018

British Journal of Surgery

View full text Add to dashboard Cite

Background: Modern advances in genetic sequencing techniques have allowed for increased availability of genetic testing for hereditary cancer syndromes. Consequently, more people are being identified as mutation carriers and becoming aware of their increased risk of malignancy. Testing is commonplace for many inheritable cancer syndromes, and with that comes the knowledge of being a gene carrier for some patients. With increased risk of malignancy, many guidelines recommend that gene carriers partake in risk reduction strategies, including risk-reducing surgery for some syndromes. This review explores the quality-of-life consequences of genetic testing and risk-reducing surgery.Methods: A narrative review of PubMed/MEDLINE was performed, focusing on the health-related quality-of-life implications of surgery for hereditary breast and ovarian cancer, familial adenomatous polyposis and hereditary diffuse gastric cancer.Results: Risk-reducing surgery almost uniformly decreases cancer anxiety and affects patients' quality of life. Conclusion:Although the overwhelming quality-of-life implications of surgery are neutral to positive, risk-reducing surgery is irreversible and can be associated with short-and long-term side-effects.

show abstract

Feasibility of laparoscopic total proctocolectomy with ileal pouch–anal anastomosis and total colectomy with ileorectal anastomosis for familial adenomatous polyposis: results of a nationwide multicenter study

Cited by 34 publications

References 41 publications

Postoperative complications after stapled and hand‐sewn ileal pouch‐anal anastomosis for familial adenomatous polyposis: A multicenter study

Postoperative complications after stapled and hand‐sewn ileal pouch‐anal anastomosis for familial adenomatous polyposis: A multicenter study

Japanese Society for Cancer of the Colon and Rectum (JSCCR) Guidelines 2016 for the Clinical Practice of Hereditary Colorectal Cancer (Translated Version)

Quality-of-life implications of risk-reducing cancer surgery

Contact Info

Product

Resources

About