Feasibility of intrafraction whole-body motion tracking for total marrow irradiation

Sharma, M. L.; Santos, Troy Dos; Papanikolopoulos, Nikolaos; Song, Hui

doi:10.1117/1.3575645

Cited by 2 publications

(1 citation statement)

References 34 publications

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“…So, clinical applications of Cherenkov imaging are expected to be increased substantially, including real-time monitoring of radiation field relative to treated patient anatomy in real-time. Overall, because of the non-ionizing feature and real-time performance with a large FOV, the OSI technology offers many surface-guided functionalities to help and facilitate clinical operations and workflow (Brahme et al 2008, Sharma et al 2011, Hoisak and Pawlicki 2018, Freislederer et al 2020.…”

Section: Other Clinical Applications Using Osimentioning

confidence: 99%

Advances and potential of optical surface imaging in radiotherapy

Li¹

2022

Phys. Med. Biol.

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This article reviews the recent advancements and future potentials of optical surface imaging (OSI) in clinical applications as a four-dimensional (4D) imaging modality for surface-guided radiotherapy (SGRT), including OSI systems, clinical SGRT, and OSI-based clinical research. The OSI is a non-ionizing radiation imaging modality, offering real-time 3D surface imaging with a large field of view (FOV) suitable for in-room interactive patient setup and real-time motion monitoring during radiotherapy. So far, most clinical SGRT applications have focused on treating superficial breast cancer or deep-seated brain cancer in rigid anatomy, because the skin surface can serve as tumor surrogates and the procedures for breast treatments with deep-inspiration breath-hold (DIBH) and cranial stereotactic radiosurgery (SRS) and radiotherapy (SRT) are well developed. When using the skin surface as a body-position surrogate, SGRT promises to replace traditional tattoo-based setup, but radiographical image-guided radiotherapy (IGRT) is still necessary, especially for stereotactic body radiotherapy (SBRT). SGRT studies in other anatomical sites have shown slightly better accuracy and performance than tattoo-based setup. To infer internal tumor motion, recent studies have shown the clinical potential of OSI-based spirometry to measure dynamic tidal volume as a tumor motion surrogate and Cherenkov surface imaging to guide and assess treatment delivery. As OSI provides complete datasets of body position, deformation, and motion, it offers an opportunity to replace fiducial-based optical tracking systems. Therefore, SGRT has great potentials for further clinical applications. In this review, the OSI technology, applications, and potentials are discussed since its first introduction to radiotherapy in 2005, including technical characterization, different commercial systems, and major clinical applications, including clinical implementation of tattoo-less SGRT. The clinical research for OSI-based tumor tracking is reviewed, including OSI-based spirometry to feed a tumor tracking model. After all, the ongoing clinical research has created more SGRT opportunities for clinical applications beyond the current scope.

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Section: Other Clinical Applications Using Osimentioning

confidence: 99%

Advances and potential of optical surface imaging in radiotherapy

Li¹

2022

Phys. Med. Biol.

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Total Body Irradiation with Step Translation and Dynamic Field Matching

Chen

Chuang

et al. 2013

BioMed Research International

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The purpose of this study is to develop a total body irradiation technique that does not require additional devices or sophisticated processes to overcome the space limitation of a small treatment room. The technique aims to deliver a uniform dose to the entire body while keeping the lung dose within the tolerance level. The technique treats the patient lying on the floor anteriorly and posteriorly. For each AP/PA treatment, two complementary fields with dynamic field edges are matched over an overlapped region defined by the marks on the body surface. A compensator, a spoiler, and lung shielding blocks were used during the treatment. Moreover, electron beams were used to further boost the chest wall around the lungs. The technique was validated in a RANDO phantom using GAFCHROMIC films. Dose ratios at different body sites along the midline ranged from 0.945 to 1.076. The dose variation in the AP direction ranged from 96.0% to 104.6%. The dose distribution in the overlapped region ranged from 98.5% to 102.8%. Lateral dose profiles at abdomen and head revealed 109.8% and 111.7% high doses, respectively, at the body edges. The results confirmed that the technique is capable of delivering a uniform dose distribution to the midline of the body in a small treatment room while keeping the lung dose within the tolerance level.

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Feasibility of intrafraction whole-body motion tracking for total marrow irradiation

Cited by 2 publications

References 34 publications

Advances and potential of optical surface imaging in radiotherapy

Advances and potential of optical surface imaging in radiotherapy

Total Body Irradiation with Step Translation and Dynamic Field Matching

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