Feasibility of diffusion weighted MR imaging in differentiating recurrent laryngeal carcinoma from radionecrosis

Gouhar, Ghada K.; El-Hariri, Mona A.

doi:10.1016/j.ejrnm.2011.05.010

Cited by 13 publications

(22 citation statements)

References 17 publications

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“…Table shows the result of the quality assessment according to the QUADAS‐2 tool of diagnostic studies . One study scored all 7 items as having a low risk of bias and applicability concerns, whereas 4 studies scored 5 or fewer items as having a low risk of bias and applicability concerns .…”

Section: Resultsmentioning

confidence: 99%

“…All studies, except Dirix et al, scored high risk of bias on the “Index test.” Although the radiologist was often blinded to the pathology when making the delineation, the ADC threshold for a positive test was determined afterward and derived from own data. Although all studies had an appropriate reference standard, 4 studies did not perform the same reference sets in all patients . Overall, the quality of the 10 articles varied from intermediate to good, according to the QUADAS‐2 tool.…”

Section: Resultsmentioning

confidence: 99%

“…An exception was Sakamoto et al, using a split acquisition of fast spin‐echo signals (SPLICE) sequence and a maximal b‐value of 771. There was wide variation in calculation of the lesions' mean ADC; some studies calculated mean ADC of the whole tumor volume, whereas other studies used the mean ADC of 1 axial slice or even a region of interest (ROI) within the tumor . The studies varied in inclusion or exclusion of necrotic or cystic parts of the lesion.…”

Section: Resultsmentioning

confidence: 99%

“…Four articles studied the diagnostic accuracy of DWI in detection of recurrent HNSCC after treatment . Vandecaveye et al supplied additional data at our request.…”

Section: Resultsmentioning

confidence: 99%

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Diffusion-weighted imaging in head and neck squamous cell carcinomas: A systematic review

et al. 2014

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…Four articles studied the diagnostic accuracy of DWI in detection of recurrent HNSCC after treatment . Vandecaveye et al supplied additional data at our request.…”

Section: Resultsmentioning

confidence: 99%

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Diffusion-weighted imaging in head and neck squamous cell carcinomas: A systematic review

et al. 2014

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“…Eight studies were judged as unclear risk because it was unclear whether the results of the index test were known during the interpretation of the reference standard [16,20,21,24–28]. The remaining four studies were considered to be at low risk of bias [17,22,23,29].…”

Section: Resultsmentioning

confidence: 99%

Diagnostic accuracy of magnetic resonance imaging techniques for treatment response evaluation in patients with head and neck tumors, a systematic review and meta-analysis

et al. 2017

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BackgroundNovel advanced MRI techniques are investigated in patients treated for head and neck tumors as conventional anatomical MRI is unreliable to differentiate tumor from treatment related imaging changes.PurposeAs the diagnostic accuracy of MRI techniques to detect tumor residual or recurrence during or after treatment is variable reported in the literature, we performed a systematic meta-analysis.Data sourcesPubmed, EMBASE and Web of Science were searched from their first record to September 23th 2014.Study selectionStudies reporting diagnostic accuracy of anatomical, ADC, perfusion or spectroscopy to identify tumor response confirmed by histology or follow-up in treated patients for head and neck tumors were selected by two authors independently.Data analysisTwo authors independently performed data extraction including true positives, false positives, true negatives, false negatives and general study characteristics. Meta-analysis was performed using bivariate random effect models when ≥5 studies per test were included.Data synthesisWe identified 16 relevant studies with anatomical MRI and ADC. No perfusion or spectroscopy studies were identified. Pooled analysis of anatomical MRI of the primary site (11 studies, N = 854) displayed a sensitivity of 84% (95%CI 72–92) and specificity of 82% (71–89). ADC of the primary site (6 studies, N = 287) showed a pooled sensitivity of 89% (74–96) and specificity of 86% (69–94).LimitationsMain limitation are the low, but comparable quality of the included studies and the variability between the studies.ConclusionsThe higher diagnostic accuracy of ADC values over anatomical MRI for the primary tumor location emphases the relevance to include DWI with ADC for response evaluation of treated head and neck tumor patients.

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Diffusion‐Weighted MRI for Recurrent/Persistent Head and Neck Squamous‐Cell Carcinoma After Radiotherapy: Systematic Review and Meta‐Analysis

Canali,

Costantino,

Mari

et al. 2024

Otolaryngol.--head neck surg.

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ObjectiveTo evaluate the accuracy of diffusion‐weighted magnetic resonance imaging (DWI‐MRI) in diagnosing persistent/recurrent head and neck squamous cell carcinomas (HNSCCs) after primary chemoradiotherapy (CRT).Data SourcesScopus, PubMed/MEDLINE, and Cochrane Library databases were searched for relevant publications until April 18, 2023.Review MethodsA systematic review and meta‐analysis was performed according to the Preferred Reporting Items for Systematic Reviews and Meta‐analyses of Diagnostic Test Accuracy statement. The search was conducted independently by 2 investigators. Methodological quality of included studies was assessed using the Quality Assessment of Diagnostic Studies‐2 questionnaire. Extracted data were used to calculate the pooled DWI‐MRI sensitivity, specificity, diagnostic odds ratio, and positive and negative likelihood ratio.ResultsA total of 618 patients from 10 studies were included for calculation of diagnostic accuracy parameters. At the level of the primary tumor, the pooled sensitivity and specificity were, respectively, 0.96 (95% confidence interval [CI]: 0.89‐1.00) and 0.81 (95% CI: 0.54‐0.98) in the case of qualitative analysis, and, respectively, 0.79 (95% CI: 0.66‐0.89) and 0.88 (95% CI: 0.77‐0.96) for quantitative analysis. At the level of the neck, the pooled sensitivity and specificity were, respectively, 0.87 (95% CI: 0.75‐0.95) and 0.84 (95% CI: 0.74‐0.93) when images were analyzed qualitatively, and 0.79 (95% CI: 0.60‐0.94) and 0.90 (95% CI: 0.82‐0.97) when analyzed quantitatively.ConclusionDWI‐MRI showed high diagnostic accuracy and should be considered if persistent/recurrent HNSCCs is suspected after primary CRT. No significant differences were found between qualitative and quantitative imaging assessment.

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Feasibility of diffusion weighted MR imaging in differentiating recurrent laryngeal carcinoma from radionecrosis

Cited by 13 publications

References 17 publications

Diffusion-weighted imaging in head and neck squamous cell carcinomas: A systematic review

Diffusion-weighted imaging in head and neck squamous cell carcinomas: A systematic review

Diagnostic accuracy of magnetic resonance imaging techniques for treatment response evaluation in patients with head and neck tumors, a systematic review and meta-analysis

Diffusion‐Weighted MRI for Recurrent/Persistent Head and Neck Squamous‐Cell Carcinoma After Radiotherapy: Systematic Review and Meta‐Analysis

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