Feasibility of bispectral index monitoring to guide early post-resuscitation cardiac arrest triage

Bispectral Index to Predict Neurological Outcome Early After Cardiac Arrest

“…These findings are in line with previous reports and confirm the ability of BIS to be an early predictor of outcome after cardiac arrest. [14][15][16][17] We also showed that there is no improved accuracy for outcome prediction using minute-by-minute data as neither specificity, nor sensitivity, nor earliness of prediction were improved compared to the method referring to BIS monitoring every 30 minutes. An explanation might be that minute-by-minute values do not add further information as there are fluctuations without relevance that nevertheless render calculations of prediction models more laborious.…”

“…anesthesia, has potential to predict outcome early after cardiac arrest. [13][14][15][16][17] In these studies, either BIS value monitored at a single time-point or the lowest recorded BIS value were considered in prediction analyses.…”

The role and limitations of EEG‐based depth of anaesthesia monitoring in theatres and intensive care

“…Mean BIS values in the first 24 h after resuscitation are higher in patients with good outcomes compared with those with poor outcomes . A retrospective evaluation of patients resuscitated from cardiac arrest showed that a form of ‘neurocardiac triage’ based on very early BIS values is feasible, and may identify patients appropriate for individualised postresuscitation care . In their cohort of 171 patients, those with a BIS < 10 suffered 91% overall mortality (82% due to neurological causes) while BIS > 20 was associated with 36% overall mortality (12% due to neurological causes).…”

The validation of simplified EEG derived from the bispectral index monitor in post-cardiac arrest patients

“…Numerous studies have already investigated BIS monitoring to assist in neurological prognostication after CA. 14,15,26 Furthermore, it has been suggested that the BIS monitor might be used to detect non-convulsive seizures as their occurrence is accompanied with fluctuations of the BIS value. [27][28][29][30] In fact, the BIS monitor samples raw EEG tracings to provide the real-time BIS value.…”

“…13 Although the BIS monitor, with incorporated BIS value calculation (0 -100), is developed to measure the depth of consciousness during general anaesthesia, several studies have used the BIS value to guide neurological prognostication after CA. 14,15 The overall goal of this study, however, was to validate retrospectively simplified raw EEG tracings derived from the BIS monitor against standard EEG monitoring in order to identify seizures and other ominous patterns often observed in post-CA patients.…”