Feasibility of a dual detector system to perform transit dosimetry and MV imaging in-vivo

Brace, Owen J.; Alhujaili, S.; Deshpande, Shrikant; Davis, Joel; Vial, P; Metcalfe, Peter E; Rosenfeld, Anatoly B.; Petasecca, Marco

doi:10.1088/1748-0221/14/01/p01019

Cited by 3 publications

(7 citation statements)

References 29 publications

(37 reference statements)

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“…The dose per pulse dependence is then calculated as the ratio S(SSD)/S ref (SSD). A more detailed description of the method adopted is outlined by Brace et al [14]. Five repetitions of the measurement were taken, and error bars were calculated as one standard deviation.…”

Section: Dose Per Pulsementioning

confidence: 99%

“…The Philips Pinnacle 3 treatment planning system (Version 16.0) was used to calculate the predicted dose-response at the detector level using the same methodology adopted in [14]. The phantom was CT scanned and the DICOM image was padded with additional voxels to extend the field of view.…”

Section: Transit Dosimetry Characterisationmentioning

confidence: 99%

“…Two previous studies have proposed dual detector systems [13,14] where an additional detector, optimised for dosimetry, would be mechanically attached on top of the EPID. Both identified that accurate dosimetry could be performed in these conditions without the EPID negatively impacting the response of the detector, while the additional detector had minimal impact on the quality of EPID images.…”

Section: Introductionmentioning

confidence: 99%

“…Both identified that accurate dosimetry could be performed in these conditions without the EPID negatively impacting the response of the detector, while the additional detector had minimal impact on the quality of EPID images. The first study adopted an array of ionization chambers [13], while the second used a pixelated silicon detector [14]. The use of the pixelated silicon was shown to be capable of performing accurate dosimetry, that could be directly compared with the treatment planning system (TPS) for a plan delivered to a heterogeneous phantom.…”

Section: Introductionmentioning

confidence: 99%

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A Large Area Pixelated Silicon Array Detector for Independent Transit In Vivo Dosimetry

et al. 2022

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A large area pixelated silicon array detector named “MP987” has been developed for in vivo dosimetry. The detector was developed to overcome the non-water equivalent response of EPID (Electronic Portal Imaging Device) dosimetry systems, due to the shortfalls of the extensive corrections required. The detector, readout system and software have all been custom designed to be operated independently from the linac with the array secured directly above the EPID, to be used in combination with the 6 MV imaging system. Dosimetry characterisation measurements of percentage depth dose (PDD), dose rate dependence, radiation damage, output factors (OF), profile measurements, linearity and uniformity were performed. Additionally, the first pre-clinical tests with this novel detector of a transit dosimetry characterization and a collapsed IMRT (intensity-modulated radiation therapy) study are presented. Both PDD and OF measurements had a percentage difference of less than 2.5% to the reference detector. A maximum change in sensitivity of 4.3 ± 0.3% was observed after 30 kGy of gamma accumulated dose. Transit dosimetry measurements through a homogeneous Solid Water phantom had a measured dose within error of the TPS calculations, for field sizes between 3 × 3 cm2 and 10 × 10 cm2. A four-fraction collapsed IMRT plan on a lung phantom had absolute dose pass fractions between the MP987 and TPS (treatment planning system) from 94.2% to 97.4%, with a 5%/5 mm criteria. The ability to accurately measure dose at a transit level, without the need for correction factors derived from extensive commissioning data collection procedures, makes the MP987 a viable alternative to the EPID for in vivo dosimetry. This MP987 is this first of its kind to be successfully developed specifically for a dual detector application.

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Section: Dose Per Pulsementioning

confidence: 99%

Section: Transit Dosimetry Characterisationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A Large Area Pixelated Silicon Array Detector for Independent Transit In Vivo Dosimetry

et al. 2022

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“…However, fabrication of silicon sensors requires the production and implantation of wafers which limit the use of silicon to relatively small area (cm 2 ) devices. An alternative material suitable for fabrication of large area, pixellated devices with potentially a very high radiation hardness is hydrogenated amorphous silicon (a-Si:H) which is already in use in a variety of applications from photovoltaic devices [1,2], to large area x-ray imaging detectors [3][4][5].…”

Section: Introductionmentioning

confidence: 99%