Feasibility demonstration of a device for vitreous liquid biopsy incidental to intravitreal injection
Alexandre R. Tumlinson,
Jennifer M. Calara,
Dimitri T. Azar
et al.
Abstract:Purpose
VitreoDx is an experimental device enabling push-button collection of a neat vitreous liquid biopsy incidental to an intravitreal injection. We explored the ability of the device to collect a sample usable for proteomic biomarker discovery and testing.
Design
Pilot study using ex vivo human eyes.
Methods
Non-vitrectomized, human eyes from nine donors 75–91 years of age were refrigerated in BSS and used within 5 days of death. Four VitreoDx devices fitted with 25G needles, and four staked needle ins… Show more
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