Feasibility and safety of a 6-month exercise program to increase bone and muscle strength in children with juvenile idiopathic arthritis

Houghton, Kristin; Macdonald, Heather M.; McKay, Heather; Guzman, Jaime; Duffy, Ciarán M.; Tucker, Lori B.

doi:10.1186/s12969-018-0283-4

Cited by 25 publications

(19 citation statements)

References 45 publications

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“…Regular physical activities have an impact on muscular strength, physical and cardiovascular capacity, as well as psychosocial health [40, 41]. There is evidence that structured aerobic and neuromuscular training may improve exercise capacity, functional performance, and quality of life in children and adolescents with JIA [42, 43], and in adults with rheumatic inflammatory diseases [44]. A positive association between increased bone mass and physical activity during the life course, and particularly in the growth period, is found in a literature review [45].…”

Section: Discussionmentioning

confidence: 99%

Participation in school and physical education in juvenile idiopathic arthritis in a Nordic long-term cohort study

et al. 2019

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Background The aim of the study was to describe school attendance and participation in physical education in school among children with juvenile idiopathic arthritis (JIA). Methods Consecutive cases of JIA from defined geographical areas of Finland, Sweden and Norway with disease onset in 1997 to 2000 were followed for 8 years in a multi-center cohort study, aimed to be as close to population-based as possible. Clinical characteristics and information on school attendance and participation in physical education (PE) were registered. Results Participation in school and in PE was lowest initially and increased during the disease course. Eight years after disease onset 228/274 (83.2%) of the children reported no school absence due to JIA, while 16.8% reported absence during the last 2 months due to JIA. Full participation in PE was reported by 194/242 (80.2%), partly by 16.9%, and none by 2.9%. Lowest participation in PE was found among children with ERA and the undifferentiated categories. Absence in school and PE was associated with higher disease activity measures at the 8-year visit. School absence > 1 day at baseline predicted use of disease-modifying anti-rheumatic drugs, including biologics (DMARDs) (OR 1.2 (1.1–1.5)), and non-remission off medication (OR 1.4 (1.1–1.7) 8 years after disease onset. Conclusion School absence at baseline predicted adverse long-term outcome. In children and adolescents with JIA participation in school activities is mostly high after 8 years of disease. For the minority with low participation, special attention is warranted to promote their full potential of social interaction and improve long-term outcome.

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Section: Discussionmentioning

confidence: 99%

Participation in school and physical education in juvenile idiopathic arthritis in a Nordic long-term cohort study

et al. 2019

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“…For comparison, in a cohort of pediatric systemic lupus patients, the mean reported K-FSS score was 3.8 24. There was no significant improvement in fatigue scores in either the exercise or control group, but other studies have shown improvement in fatigue with exercise 25…”

Section: Discussionmentioning

confidence: 94%

“…However, home-based exercise interventions in this population have also proven to be challenging. In a study by Houghton et al, in a 6-month home-based exercise program of aerobic and resistance exercises, only 47% of children reported adherence to the program, with adherence decreasing over time 25…”

Section: Discussionmentioning

confidence: 99%

<p>Slow speed resistance exercise training in children with polyarticular juvenile idiopathic arthritis</p>

Sule

Fontaine

2019

OARRR

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Background: Juvenile idiopathic arthritis (JIA) is an inflammatory autoimmune disease that can cause severe impairment and disability. Exercise is recommended to preserve joint mobility and function. Our objectives were to assess the safety, feasibility, and effects of slow speed resistance exercise in children with polyarticular JIA. Methods: Patients were recruited from a pediatric rheumatology clinic at an urban hospital and randomized to exercise or control groups. In the intervention group, slow speed resistance exercise with individualized instruction by a certified trainer was performed 1–2 times per week for 12 weeks. The control group performed home-based aerobic exercise 3 days per week for 12 weeks. Pre and post-body composition measurements by dual-energy X-ray absorptiometry; aerobic fitness by peak oxygen uptake during cycle ergometry; isometric muscle strength; and quality of life measures were obtained. Results: In the exercise group, 9/17 (53%) completed any exercise training. Of these nine subjects, five (55%) completed all 12 weeks of the protocol. In the control group, 8/16 (50%) reported compliance with the recommended aerobic exercise training at least one time per week. Only 2 subjects (12%) reported exercising more than once per week. There was no significant difference between pre- and post-measurements in any category in the exercise group. There was also significantly elevated body fat in both groups with only 17% in the control group and 23% in the exercise group meeting recommended <30% total body fat levels. Conclusions: Children with JIA participated safely in this resistance exercise protocol. The exercise was well-tolerated with no serious adverse events noted. While individual subjects reported improvement in fatigue and improved energy, there was no statistical difference in pre- and post-exercise measures of body composition or quality of life. Identifying ways to improve adherence and encourage exercise in children with JIA is important.

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“…The JAQQ has been used to measure quality of life in a clinical trial of an exercise program (LEAP Study, Canadian Institutes of Health [Canadian Institutes of Health Research grant 107535]) (44).…”

Section: Juvenile Arthritis Quality Of Life Questionnairementioning

confidence: 99%

Measures of Health Status and Quality of Life in Juvenile Idiopathic Arthritis

Morgan

Carle

2020

Arthritis Care & Research

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Feasibility and safety of a 6-month exercise program to increase bone and muscle strength in children with juvenile idiopathic arthritis

Cited by 25 publications

References 45 publications

Participation in school and physical education in juvenile idiopathic arthritis in a Nordic long-term cohort study

Participation in school and physical education in juvenile idiopathic arthritis in a Nordic long-term cohort study

<p>Slow speed resistance exercise training in children with polyarticular juvenile idiopathic arthritis</p>

Measures of Health Status and Quality of Life in Juvenile Idiopathic Arthritis

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