“…From the eight studies examining the effect of tumor size [11,13,21,23,24,27], AL was present in 8.3 % of the patients with tumor diameter [5 cm compared to 4.9 % of the patients with tumor size B5 cm. The pooled analysis showed that the risk of AL was significantly higher in the cases of tumor size [5 cm (OR 1.63, 95 % CI 1.01-2.64, P = 0.05).…”