Feasibility and Accuracy of Left Ventricular Volumes and Ejection Fraction Determination by Fundamental, Tissue Harmonic, and Intravenous Contrast Imaging in Difficult-to-Image Patients

Yu, Eric; Sloggett, Cairrine; Iwanochko, Robert M.; Rakowski, Harry; Siu, Samuel C.

doi:10.1067/mje.2000.103597

Cited by 90 publications

(27 citation statements)

References 28 publications

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“…14,15 In Figure 4, the intra-and inter-observer variabilities for LV-EF reported in studies using SHI and LVO imaging are summarized. 14,16,17 Due to the consecutive character of patient inclusion in our study (no patient was excluded because of image quality) our SHI result seems worse than those reported by others. Although some authors showed an improvement in LV endocardial border detection with SHI compared to FI, 9 optimal intra-and inter-observer variability in LV-EF can only be achieved when contrast is added to SHI imaging.…”

Section: Discussioncontrasting

confidence: 52%

Assessment of left ventricular ejection fraction after myocardial infarction using contrast echocardiography

Galema¹,

Geleijnse²,

Yap³

et al. 2007

European Journal of Echocardiography

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Aims Despite its relatively high intra-and inter-observer variability for left ventricular ejection fraction (LV-EF) echocardiography is clinically still the most used modality to assess LV-EF. We studied whether adding a second-generation microbubble contrast agent could decrease this variability. Methods and results Forty-eight patients underwent transthoracic echocardiography in secondharmonic mode (SHI) with and without contrast within 5 days after an acute myocardial infarction. LV-EF was determined using the Simpson's biplane method. With contrast intra-observer variability decreased from 12.5 + 11.5% to 7.0 + 7.0% (P , 0.001) and inter-observer variability decreased from 16.9 + 9.9% to 7.0 + 6.2% (P , 0.001). Bland-Altman analysis confirmed these findings by demonstrating smaller 95% limits of agreement for both the intra-and inter-observer variability when contrast was used. This improvement in intra-and inter-observer variability was seen to a comparable extent in patients with moderate-to-poor and good quality SHI echocardiograms. Conclusion Echo contrast significantly improves intra-and inter-observer variability for LV-EF, both in patients with moderate-to-poor and good quality SHI echocardiograms.

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Section: Discussioncontrasting

confidence: 52%

Assessment of left ventricular ejection fraction after myocardial infarction using contrast echocardiography

Galema¹,

Geleijnse²,

Yap³

et al. 2007

European Journal of Echocardiography

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“…128 Endocardial border dropout can frequently occur in patients undergoing chemotherapy (in particular patients with breast cancer after mastectomy and chest irradiation). According to the ASE consensus statement on the clinical applications of ultrasonic contrast agents in echocardiography and EAE recommendations 129,130 on myocardial contrast echocardiography, a contrast agent should be used when two contiguous LV segments from any apical view are not seen on non-contrast images ( Figure 6).…”

Section: G Contrast Echocardiographymentioning

confidence: 99%

Expert Consensus for Multimodality Imaging Evaluation of Adult Patients during and after Cancer Therapy: A Report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging

Plana

Galderisi

Barac

et al. 2014

Journal of the American Society of Echocardiography

1,284

1,209

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“…In only 3 patients was a single acquisition of insufficient quality. Previous studies have shown an improvement in image quality [24] and, subsequently, smaller limits of agreement in inter- and intra-observer variability when intravenous ultrasound contrast agents are used [25, 26]. Further studies are necessary to evaluate the feasibility thereof in this patient population.…”

Section: Discussionmentioning

confidence: 99%

Three-Dimensional Echocardiographic Analysis of Left Ventricular Function during Hemodialysis

et al. 2007

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Background: The effects of hemodialysis (HD) on left ventricular (LV) function have been studied by various echocardiographic techniques (M-mode, 2D echocardiography). These studies are hampered by a low accuracy of measurements because of geometric assumptions regarding LV shape. Three-dimensional echocardiography (3DE) overcomes this limitation. Methods: We tested the feasibility of 3DE assessment of LV function during HD. Conventional biplane Simpson rule (BSR) and single plane area length method (SPM) for LV function analysis were used as a reference. Results: 12 HD patients were studied and in 10 (83%) a total of 80 3D datasets were acquired. In 3 patients, one dataset (4%) was of insufficient quality and excluded from analysis. Correlation between SPM, BSR and 3DE for calculation of end-diastolic (EDV, r = 0.89 and r = 0.92, respectively), end-systolic volume (ESV, r = 0.92 and r = 0.93, respectively) and for ejection fraction (EF, r = 0.90 and r = 0.88, respectively) was moderate. Limits-of-agreement results for EDV and ESV were poor with confidence intervals larger than 30 ml. Both 2DE methods underestimated end-diastolic and end-systolic volume, while overestimating ejection fraction. Conclusion: 3DE is feasible for image acquisition during HD, which opens the possibility for accurate and reproducible measurement of LV function during HD. This may improve the assessment of the acute effect of HD on LV performance, and guide therapeutic strategies aimed at preventing intradialytic hypotension.

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Feasibility and Accuracy of Left Ventricular Volumes and Ejection Fraction Determination by Fundamental, Tissue Harmonic, and Intravenous Contrast Imaging in Difficult-to-Image Patients

Cited by 90 publications

References 28 publications

Assessment of left ventricular ejection fraction after myocardial infarction using contrast echocardiography

Assessment of left ventricular ejection fraction after myocardial infarction using contrast echocardiography

Expert Consensus for Multimodality Imaging Evaluation of Adult Patients during and after Cancer Therapy: A Report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging

Three-Dimensional Echocardiographic Analysis of Left Ventricular Function during Hemodialysis

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