Feasibility and accuracy of gated blood pool SPECT equilibrium radionuclide ventriculography for the assessment of left and right ventricular volumes and function in patients with left ventricular assist devices

Abstract

t-ERV is a simple, reproducible, and an accurate technique for the assessment of RV function in patients with LVADs and warrants consideration in the evaluation and monitoring of symptomatic patients.

Determinants of Functional Capacity and Quality of Life After Implantation of a Durable Left Ventricular Assist Device

“…Postimplantation mean pVO 2 values ( Figure 2B ) vary from 8.8 to 21.4 ml/kg/min (mean pVO 2 weighted for population size 13.2 ml/kg/min), showing that pVO 2 generally remains reduced after implantation at, on average, 48% of the expected value for age and sex. [ 12 – 16 , 21 – 23 , 25 – 29 , 31 – 37 , 39 – 42 , 44 – 47 , 61 – 63 ] A considerable proportion of the variance of postimplantation pVO 2 between published studies can be attributed to differences in the mean age of included patients. [ 11 ]…”

“…The mean walking distance after implantation with a sole LVAD was 370 m (182 days after implantation; range 43–543 days). The number of patients included in each study or study arm, as stated, is indicated by the size of the circles, with the exception of Lairez et al[ 39 ] in which n for both shown study arms is set to 18, which is in fact the total study n. The mean 6MWT distance weighted for population size was 354 m. B: Studies reporting on peak oxygen uptake (pVO 2 ). The mean reported pVO 2 was 13.4 ml/kg/min or 48% of predicted pVO 2 (values not shown).…”

Assessment of right ventricular sympathetic dysfunction in patients with arrhythmogenic right ventricular cardiomyopathy: An 123I-metaiodobenzylguanidine SPECT/CT study

“…21 Complementary nuclear medicine techniques like gated SPECT equilibrium radionuclide angiocardiography can be used to calculate ventricular functions, volumes, synchrony, and entropy or regional wall motion abnormalities. This techniques could be helpful in identifying patients with suspected ARVC/D [22][23][24] and should be further evaluated in the future to enable a faster and more reliable diagnosis in this rare but endangered cohort.…”

Equilibrium radionuclide angiography: Present and future

“…Table 1 shows the reproducibility, and inter-and intra-observer variations of ERNA according to different acquisition methodology to evaluate left and right ventricular function. [1][2][3][4][5][6][7] ERNA has a high reproducibility, very low inter-or intra-observer variability, and high precision; it has been shown to be accurate when compared to other modalities and has strong early data that demonstrated efficacy in guiding the safety of treatment regimens, and it continues to be widely used for routine clinical monitoring. 8 This information is consistent with the comments of Sachpekidis et al 9…”