Feasibility and accuracy of a routine echocardiographic assessment of right ventricular function

Tamborini, Gloria; Pepi, Mauro; Galli, C.; Maltagliati, Anna; Celeste, Fabrizio; Muratori, Manuela; Salehi, Roya; Veglia, Fabrizio

doi:10.1016/j.ijcard.2006.01.017

Cited by 116 publications

(81 citation statements)

References 19 publications

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“…In the present study, TAPSE acquired on CMR images showed comparable normal ranges with previous studies in echocardiography [25,26], thus the described method for CMR seems valid. The reason for a higher level of correlation between TAPSE and RV EF in the present study may be a larger study population with a wider range of RV parameters than previously investigated.…”

Section: Discussionsupporting

confidence: 89%

Semi-quantitative assessment of right ventricular function in comparison to a 3D volumetric approach: A cardiovascular magnetic resonance study

et al. 2008

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Semi-quantitative assessment of right ventricular function in comparison to a 3D volumetric approach: A cardiovascular magnetic resonance study Abstract Right ventricular (RV) volume measurements with cardiovascular magnetic resonance (CMR) is considered the gold standard, but acquisition and analysis remain timeconsuming. The aim of our study was therefore to investigate the accuracy and performance of a semi-quantitative assessment of RV function in CMR, compared to the standard quantitative approach. Seventy-five subjects with pulmonary hypertension (15), anterior myocardial infarction (15), inferior myocardial infarction (15), Brugada syndrome (15) and normal subjects (15) underwent cine CMR. RV end-systolic and enddiastolic volumes were determined to calculate RV ejection fraction (EF). Four-chamber cine images were used to measure tricuspid annular plane systolic excursion (TAPSE). RV fractional shortening (RVFS) was calculated by dividing TAPSE by the RV end-diastolic length. RV EF correlated significantly with TAPSE (r = 0.62, p < 0.01) and RVFS (r = 0.67, p < 0.01). Sensitivity to predict RV dysfunction was comparable between TAPSE and RVFS, with higher specificity for RVFS, but comparable areas under the ROC curve. Intra-and inter-observer variability of RV EF was better than TAPSE (3%/4% versus 7%/15%, respectively). For routine screening in clinical practice, TAPSE and RVFS seem reliable and easy methods to identify patients with RV dysfunction. The 3D volumetric approach is preferred to assess RV function for research purposes or to evaluate treatment response.

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Section: Discussionsupporting

confidence: 89%

Semi-quantitative assessment of right ventricular function in comparison to a 3D volumetric approach: A cardiovascular magnetic resonance study

et al. 2008

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“…); reproducibility was excellent for LV mass ( r =0.98; P <0.001; CV=6.1%), LVEF ( r =0.83; P =0.003; CV=3.0%), cardiac output ( r =0.91; P <0.001; CV=7.9%); LA volume ( r =0.92; P <0.001; CV=10.3%), pulmonary artery systolic pressure ( r =0.92; P <0.001; CV=7.3%), RV end‐diastolic area ( r =0.96; P <0.001; CV=4.8%), RA area ( r =0.92; P <0.001; CV=7.2%), PVR ( r =0.92; P <0.001; CV=5.4%), and TAPSE ( r =0.83; P <0.005; CV=6.0%). These results are within the desirable reproducibility for ECG outcome variables used in clinical trials or observational studies 32, 38, 39…”

Section: Methodssupporting

confidence: 57%

Treatment of Obstructive Sleep Apnea in Young and Middle‐Aged Adults: Effects of Positive Airway Pressure and Compliance on Arterial Stiffness, Endothelial Function, and Cardiac Hemodynamics

Korcarz

Benca

Barnet

et al. 2016

JAHA

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BackgroundThe cardiovascular effects of positive airway pressure (PAP) therapy in obstructive sleep apnea (OSA) patients are not clear because of confounding by comorbid conditions.Methods and ResultsProspective interventional study of PAP therapy and withdrawal. Apnea Hypopnea Index (AHI; events/hour of sleep) was determined from polysomnography. Central aortic blood pressures (BPs), Aortic Augmentation Index (AAIx), and central (PWV c‐f) and peripheral pulse wave (PWV c‐r) velocities were determined by applanation tonometry. Echocardiography and brachial artery reactivity testing were performed at baseline, after 4 and 12 weeks of PAP therapy, and 1 week after PAP withdrawal. The 84 participants were mean (SD) 41.1 (7.6) years old and had 39.8 (24.5) AHI events/hour. After 4 weeks post‐PAP initiation and sustained after 12 weeks, subjects experienced decreases in central systolic BP (P=0.008), diastolic BP, mean BP, AAIx, and PWV c‐r, and brachial artery dilation (all P<0.001), as well as improvements in left ventricular diastolic function and systemic and pulmonary vascular resistance. In adjusted models, PAP use (hours/night) predicted reductions in diastolic BP (β=−0.65 [SE, 0.32] mm Hg/hour; P=0.045), AAIx (β=−0.53 [0.27] %/hour; P=0.049) and PWV c‐r (β=−0.13 [0.05] m·s−1/hour; P=0.007), and improved brachial artery flow‐mediated dilation (β=0.31 [0.14] %/hour use; P=0.015). After 1 week of PAP withdrawal, brachial diameter, diastolic BP, mean BP, AAIx, and heart rate increased (P≤0.05).Conclusions PAP therapy reduces arterial tone and improves endothelial and diastolic function in young to middle‐aged adults. This positive effect is observed after 4 weeks and depends on hours of use, but reverts quickly with PAP withdrawal.Clinical Trial RegistrationURL: https://clinicaltrials.gov/. Unique identifier: NCT01317329.

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“…Patients who had RV dysfunction were significantly older compared to those who had normal RV function. This finding is concordant with the study by Gloria Tamborini et al [6] which concluded TAPSE was negatively related with age, and also with the study of Zornoff et al [3] No significant difference noted with regards to gender distribution, frequency of hypertension, diabetes, smoking or other forms of tobacco usage in patients with or without RV dysfunction. These observations were similar to those of Zornoff et al [3] in their study of 416 patients with acute MI.…”

Section: Discussionsupporting

confidence: 91%

Assessment of Right Ventricular Function in Acute St-Elevation Myocardial Infarction by Echocardiography

Krishna¹

2017

jemds

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BACKGROUNDRight Ventricular (RV) function has been shown to be a major determinant of clinical outcome and consequently should be considered during clinical management and treatment. Thus, the need for diagnosis of RV dysfunction is evident. MATERIALS AND METHODS RESULTSIncidence of RV dysfunction in study population by TAPSE<1.5 cm was 44 (22%). 23 (29.1%) patients with Inferior wall MI had RV dysfunction and 21 (17.3%) patients with anterior wall MI had RV dysfunction. Out of 200 patients with acute myocardial infarction, 22% (44/200) had RV dysfunction. Mean age of patients in RV dysfunction group was 57.4 ± 11.3 years and of patients in no-RV dysfunction (Normal RV function) group was 52.3 ± 11.2 years (p =0.008). 15.9% (7/44) patients in RV dysfunction group had past history of Coronary artery disease compared to 5.8% (9/156) in normal RV function group (p=0.02). CONCLUSIONNearly one fourth of patients with Acute ST-Elevation Myocardial Infarction had right ventricular dysfunction. LV dysfunction contributes significantly to RV dysfunction in acute myocardial infarction more so in anterior wall MI. KEYWORDS BACKGROUNDRight Ventricular (RV) function may be impaired either by primary right-sided heart disease, or secondary to left-sided cardiomyopathy or valvular heart disease. In addition, it should be considered that RV dysfunction may affect left ventricular (LV) function, not only by limiting LV preload, but also by adverse systolic and diastolic interaction via the interventricular septum and the pericardium (ventricular interdependence). Moreover, RV function has been shown to be a major determinant of clinical outcome and consequently should be considered during clinical management and treatment. Thus, the need for diagnosis of RV dysfunction is evident.

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Feasibility and accuracy of a routine echocardiographic assessment of right ventricular function

Cited by 116 publications

References 19 publications

Semi-quantitative assessment of right ventricular function in comparison to a 3D volumetric approach: A cardiovascular magnetic resonance study

Semi-quantitative assessment of right ventricular function in comparison to a 3D volumetric approach: A cardiovascular magnetic resonance study

Treatment of Obstructive Sleep Apnea in Young and Middle‐Aged Adults: Effects of Positive Airway Pressure and Compliance on Arterial Stiffness, Endothelial Function, and Cardiac Hemodynamics

Assessment of Right Ventricular Function in Acute St-Elevation Myocardial Infarction by Echocardiography

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