In the last 6 decades, large sections of the global population have been exposed to ongoing dangers in circumstances of pervasive conflict, violence and trauma. In this article, we revisit the concept of continuous traumatic stress, originally proposed by South African researcher-practitioners to characterize mental health conditions and challenges under apartheid, and explore its viability as an alternative and supplementary framework for understanding and addressing exposure to situations of ongoing threat. The article highlights the political and mental health limitations associated with the dominance of posttraumatic stress conceptualizations of these forms of human suffering and distress, and calls for more nuanced and complex understandings of such complicated psychosocial conditions and their effects. It concludes by foregrounding several critical debates related to continuous traumatic stress, namely, the importance of understanding contexts of ongoing exposure to danger as both political and psychological (psychopolitical) in nature; of developing socially relevant clinical and conceptual models that can meaningfully account for the varied impacts of, and responses to, these conditions of continuous threat; and the need to extend our intervention practices to include culturally and contextually appropriate intervention strategies that are both clinical and psychosocial in orientation.