Fe3O4 Coated SiO2 Magnetic Nanoparticles for Enhanced Antibacterial Activity and Electrochemical Sensing

Abstract

Multifunctional magnetic composite nanoparticles (NPs) with antibiotics have demonstrated symbiotic effects because of their promising antimicrobial properties. The antimicrobial agent reduces side effects and dosage, and increases drug delivery efficiency. In this study, SiO2 coated over Fe3O4 magnetic nanoparticles (MNPs) were prepared by a solvothermal method. The MNPs were characterized by using X-ray diffraction (XRD), transmission electron microscopy (TEM), ultraviolet-visible spectroscopy (UV-vis), and Fourier transform infrared spectroscopy (FTIR). The antimicrobial tests were carried out using the disk diffusion method. The electrochemical sensing was investigated by cyclic voltammetry with varying As(III) concentrations from 1–10 ppb. The microstructural results showed the formation of spherical-shaped Fe3O4@SiO2 MNPs with 15–30 nm diameters. UV-vis results showed that Fe3O4 NPs promote visible light absorption of Fe3O4@SiO2 MNPs because of well-structured and unvarying shell thickness which is beneficial for the absorption of organic dyes. With an increase in the concentration of As(III), there was a shift in potential and an increase in oxidation peak current, showing the electrocatalytic capacity of the modified electrode. The SiO2 deposited on Fe3O4 displayed an admirable microbial operation. These Fe3O4@SiO2 MNPs are easily absorbed by cells and have the potential to influence bacterial cells both within and outside of the cell membrane, making them an intriguing candidate for use in a variety of biological applications in the future.

Enhancement in the induction heating efficacy of sol–gel derived SiO2–CaO–Na2O–P2O5 bioglass-ceramics by incorporating magnetite nanoparticles

“…The magnetic properties of SiO 2 -CaO-Na 2 O-P 2 O 5 -Fe 2 O 3 glasses and glass-ceramics, and SiO 2 coated Fe 3 O 4 core-shell nanoparticles have been investigated towards biomedical applications. [12][13][14]17,18,[41][42][43][44][45][46][47][48][49][50][51][52][53][54][55][56] A survey of the literature shows that the magnetic properties of the above systems depend strongly on their composition and synthesis route. Rehman et al reported a sol-gel derived mesoporous magnetic glass-ceramic with a composition of 7Fe 3 O 4 -51SiO 2 -18CaO-20Na 2 O-4P 2 O 5 (mol%) containing Fe 3 O 4 with average particle size of 50 AE 10 nm and M s of B13 emu g À1 .…”

“…11 Silica-coated magnetite nanoparticles have been extensively studied for various biomedical applications, including magnetic hyperthermia. [12][13][14][15][16][17][18] The cytotoxicity and magnetic properties of iron oxide-based 58S (58SiO 2 -33CaO-9P 2 O 5 ) bioactive glass and glass-ceramics have been investigated towards application in MHT. 19,20 Several ceramic compositions containing iron oxide have been reported.…”

Hybrid Metal Oxide Nanocomposites for Gas-Sensing Applications: A Review

“…MEMS gas sensors are widely recognized to have a variety of applications because of their capacity for downsizing . Electrochemical, optical, and acoustic MEMS gas sensor types have all been created. , Different electrochemical gas sensors, including MOS and chemiresistive gas sensors, are employed in the detection of stomach infections and diabetes in addition to the monitoring of industrial gases. Higher sensitivity, low power consumption, multigas detection, selectivity to different gases, smaller designs, and lower production costs are some of its advantages over traditional gas sensors. ,,− …”