Fe₃O₄@Au–metal organic framework nanozyme with peroxidase-like activity and its application for colorimetric ascorbic acid detection

Abstract

The free radical scavenging system based on Fe3O4@Au/MOF-ABTS•+ has developed a novel method for the high sensitivity and specificity spectrophotometric determination of ascorbic acid (AA). The Fe3O4@Au/MOF nanozyme with magnetic...

Enhanced Peroxidase-Mimic Catalytic Activity via Cerium Doping of Strontium-Based Metal–Organic Frameworks with Design of a Smartphone-Based Sensor for On-Site Salivary Total Antioxidant Capacity Detection in Lung Cancer Patients

“…In addition to providing routes for the mass movement of reactants and products, the large surface area of MOFs facilitates the appropriate exposure of active areas. These characteristics make MOFs very well-suited for heterogeneous catalysis. − Recently, MOFs with an inherent enzymelike activity have been designed for the detection of TAC, such as CuBDC@Fe­(III)-ART NPs, Fe 3 O 4 @Au–MOFs, and Tα-MOF . Although organic linkers with terminal carboxylate groups are frequently used in MOF synthesis, only a few strontium-based compounds have been identified to a considerable extent.…”

Vanadium‐Incorporated Mesoporous Silica as Oxidase Mimic for Colorimetric Dopamine Detection and Anticancer Activity

“…Nanomaterials with enzyme‐like properties (nanozymes) have provoked researchers′ curiosity worldwide because of their ease of preparation, scale‐up, extended storage length, excellent stability, broad pH/temperature tolerance compared to bio‐enzymes, and low‐cost availability [11–13] . This nanostructured material can detect a wide range of metabolites by mimicking enzyme functions such as oxidase, peroxidase, catalase, and superoxide dismutase without having any structural resemblance to natural enzymes [14–21] . Peroxidase‐like biomimics are the most well‐studied inorganic nanozymes for bioanalytes detection and immunoassay applications [22] .…”

“…[11][12][13] This nanostructured material can detect a wide range of metabolites by mimicking enzyme functions such as oxidase, peroxidase, catalase, and superoxide dismutase without having any structural resemblance to natural enzymes. [14][15][16][17][18][19][20][21] Peroxidase-like biomimics are the most well-studied inorganic nanozymes for bioanalytes detection and immunoassay applications. [22] However, using a strong oxidizing agent, H 2 O 2, in a peroxidase-like catalytic reaction is mandatory.…”

Enhancing the catalytic performance of MOF-polymer@AuNP-based nanozymes for colorimetric detection of serum l-cysteine

“…Currently, common methods 2–10 for the integration of AuNPs and MOFs are encapsulation, 2,4,5 in situ growth 3,6,8 and surface modification. 7,9,10 For example, MOF@AuNPs with a yolk–shell nanostructure were constructed via a sacrificial template strategy.…”

“…A straightforward solvothermal method was developed for the preparation of MOF@Fe 3 O 4 -AuNP composites by physical adsorption of Fe 3 O 4 -AuNPs onto the surface of the MOF. 10 The composites showed peroxidase (POD)-mimetic activity in a 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid-H 2 O 2 system. Notably, the Fe 3 O 4 -AuNPs were not uniformly dispersed on the MOF surface, leading to low catalytic activity, perhaps due to weak surface interactions arising from the aggregation of the AuNPs on the MOF surface.…”