Fe(SO₄)₃‐Catalyzed Synthesis of Terpenic Alcohols Esters: A Simple and Bifunctional Reusable Solid Catalyst

Abstract

Ferric sulfate is a simple and commercially available solid catalyst and demonstrated to be able to catalyze terpenic alcohols esterification with acetic acid, achieving high conversion and ester selectivity. This process is an attractive option to the enzymatic or acid homogenous processes commonly used to synthesize esters. The undesirable steps of neutralizing of the products are avoided. A study of the activity of hydrated Fe 2 (SO 4 ) 3 demonstrated that although the efficiency of the catalyst is directly linked to the ability of the Fe III cations to generate H 3 O + ions, the solid catalyst plays also a key role on the esterification process. We assessed the effects of the main reaction variables such as reactants proportion, temperature, and catalyst concentration. Different terpenic alcohols such as b-citronellol, geraniol, nerol, linalool, a-terpineol and borneol were esterified in the presence of Fe 2 (SO 4 ) 3 catalyst. The Fe 2 (SO 4 ) 3 catalyst was easily recovered and reused.[a] Prof.