Fe-doped mesoporous silica catalyzes ascorbic acid oxidation for tumor-specific therapy in scaffold

Shuai, Cijun; Chen, Xuan; He, Chongxian; Chen, Min; Peng, Shuping; Yang, Wenjing

doi:10.1016/j.colsurfb.2023.113251

Cited by 5 publications

(1 citation statement)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Ca 2+ could directly act on mitochondria, [48][49][50] affect their normal functions, and stimulate the changes of mitochondrial membrane potential and ATP production. L-AA did not directly act on mitochondria; on the other hand, it indirectly changes the redox equilibrium state in tumor cells through pro-oxidation, 22,23,51 which could further result in an imbalance of cell metabolism. In this design, CaP-AA acted on the tumor cells with the combination of direct and indirect effects, by affecting the functional organelle mitochondria, and nally inducing damage to tumor cells.…”

Section: Discussionmentioning

confidence: 92%

Responsive calcium-derived nanoassemblies induce mitochondrial disorder to promote tumor calcification

Zhao,

Yu,

Kong

et al. 2023

Chem. Sci.

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 92%

Responsive calcium-derived nanoassemblies induce mitochondrial disorder to promote tumor calcification

Zhao,

Yu,

Kong

et al. 2023

Chem. Sci.

View full text Add to dashboard Cite

show abstract

Recent Advances in 3D Printing of Smart Scaffolds for Bone Tissue Engineering and Regeneration

Yuan,

Zhu,

Yang

et al. 2024

Advanced Materials

View full text Add to dashboard Cite

The repair and functional reconstruction of bone defects resulting from severe trauma, surgical resection, degenerative disease, and congenital malformation pose significant clinical challenges. Bone tissue engineering (BTE) holds immense potential in treating these severe bone defects, without incurring prevalent complications associated with conventional autologous or allogeneic bone grafts. 3D printing technology enables control over architectural structures at multiple length scales and has been extensively employed to process biomimetic scaffolds for BTE. In contrast to inert and functional bone grafts, next‐generation smart scaffolds possess a remarkable ability to mimic the dynamic nature of native extracellular matrix (ECM), thereby facilitating bone repair and regeneration. Additionally, they can generate tailored and controllable therapeutic effects, such as antibacterial or antitumor properties, in response to exogenous and/or endogenous stimuli. This review provides a comprehensive assessment of the progress of 3D‐printed smart scaffolds for BTE applications. It begins with an introduction to bone physiology, followed by an overview of 3D printing technologies utilized for smart scaffolds. Notable advances in various stimuli‐responsive strategies, therapeutic efficacy, and applications of 3D‐printed smart scaffolds are discussed. Finally, the review highlights the existing challenges in the development and clinical implementation of smart scaffolds, as well as emerging technologies in this field.

show abstract

Recent trends of biodegradable mesoporous silica based nanoplatforms for enhanced tumor theranostics

Ye,

Xu,

Jian

et al. 2024

Chinese Chemical Letters

View full text Add to dashboard Cite

Fe-doped mesoporous silica catalyzes ascorbic acid oxidation for tumor-specific therapy in scaffold

Cited by 5 publications

References 50 publications

Responsive calcium-derived nanoassemblies induce mitochondrial disorder to promote tumor calcification

Responsive calcium-derived nanoassemblies induce mitochondrial disorder to promote tumor calcification

Recent Advances in 3D Printing of Smart Scaffolds for Bone Tissue Engineering and Regeneration

Recent trends of biodegradable mesoporous silica based nanoplatforms for enhanced tumor theranostics

Contact Info

Product

Resources

About