Fe+3-Montmorillonite K10, as effective, eco-friendly, and reusable catalyst for the synthesis of bis(1H-indol-3-yl)methanes under grinding condition

Exploring Untouched Variant of Bis(2‐methyl‐1H‐indol‐3‐yl)methane: Enhances Chemo and Mono‐Selectivity

“…[3] You can directly obtain indoles with various carbonyl functional groups by using both homo-and heterogeneous catalysts. These catalysts cover a broad spectrum, encompassing acid catalysts, [4][5][6][7][8][9][10][11][12][13][14] Nano catalysts, [15][16][17][18][19][20][21] supported catalysts, [22][23][24][25][26][27][28][29][30][31][32][33][34][35] metal catalysts, [36][37][38][39][40][41][42][43] ion exchange resin, [44] and enzymes. [45] Reactions catalyzed by acids in this context involve substances such as HCl, [46] P 2 O 5 , [47] Amberlyst-15, [48] and solidified acids.…”

Promoting decanoic acid unveils the transfigure aldehyde carbonyl activation for synthesizing bis(indolyl)methane derivatives

“…Indoles with various carbonyl functional groups can be obtained directly using homo and heterogeneous catalysts. Different types of catalysts can be employed for these reactions, including acid catalysts [3][4][5][6][7][8][9][10][11][12][13], nanocatalysts [14][15][16][17][18][19][20], supported catalysts [21][22][23][24][25][26][27][28][29][30], metal catalysts [31][32][33][34][35][36][37][38], ion exchange resin [39], and enzymes [40]. The acid-catalyzed reactions can be facilitated by HCl [41], P 2 O 5 [42], Amberlyst-15 [43], and solidified acids [44].…”

Iron‐containing ionic liquid as an efficient and recyclable catalyst for the synthesis of C3‐substituted indole derivatives

“…Therefore, various methods have been reported for preparing this class of compounds . The most straightforward method to obtain the heterocycle involves the condensation of indoles with different carbonyl compounds (aldehydes or ketones), which was often promoted by homo‐ and heterogeneous catalysts such as acid catalysts, nano catalysts, supported catalysts, metal catalysts, ion exchange resin, and enzymes . Although these reported protocols have made some certain merits, many of them still have notable disadvantages such as harsh reaction conditions, long reaction times, limited substrate scope, using expensive Lewis acids and solvents, high catalyst loading and generation of large amounts of harmful wastes.…”

“…[8] Therefore, various methods have been reported for preparing this class of compounds. [9][10][11] The most straightforward method to obtain the heterocycle involves the condensation of indoles with different carbonyl compounds (aldehydes or ketones), which was often promoted by homo-and heterogeneous catalysts such as acid catalysts, [12][13][14][15][16][17][18][19][20][21][22][23][24] nano catalysts, [25][26][27][28][29][30][31] supported catalysts, [32][33][34][35][36][37][38][39][40][41] metal catalysts, [42][43][44][45][46][47][48][49] ion *These authors contributed equally to this work. exchange resin, [50] and enzymes.…”