FDX1 is a Potential Prognostic Biomarker Related to Cuproptosis and Immune Infiltration for Patients with Kidney Renal Clear Cell Carcinoma

Abstract

Objective The aim of this study was to detect the correlation between the FDX1 (Cuproptosis-related gene) expression levels and overall survival, clinical characteristics, and immune infiltration for patients with KIRC. Results The FDX1 expression levels were lower in KIRC tumor tissues. The high expression of FDX1 was a positive prognosis factor since it had a significantly positive correlation with the overall survival of patients with KIRC. Also, the FDX1 expression levels had a negative association with the immune infiltrate levels and enriched effects on inflammation and immune signaling pathways. Conclusion FDX1 was a potential Cuproptosis-related prognostic biomarker for KIRC immunotherapy.