FDG Positron Emission Tomographic Imaging of Thoracic Castleman’s Disease

Reddy, Madhusudhan P.; Graham, Michael M.

doi:10.1097/01.rlu.0000057615.73933.2f

Cited by 20 publications

(6 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Patients, themselves, often recognize cervical, inguinal or axillary involvement which is then brought to the attention of their health care provider. U‐HVV lesions most often present as solitary masses with intense homogeneous contrast enhancement on computed tomography (CT) (Ko et al , 2004) and positron emission tomography may not be useful for distinguishing CD from malignancy (Reddy & Graham, 2003). In contrast to the plasma cell and multicentric variants of CD, U‐HVV is rarely (<10%) associated with systemic symptoms.…”

Section: Unicentric Hyaline Vascular Variant (U‐hvv)mentioning

confidence: 99%

The aetiology and management of Castleman disease at 50 years: translating pathophysiology to patient care

2005

View full text Add to dashboard Cite

SummaryFifty years ago, Dr Benjamin Castleman first described the unusual lymphoproliferative disorder that now bears his name. Over the subsequent decades, astute clinical and pathologic observations coupled with clever molecular biologic research have increased our understanding of the aetiology of Castleman disease (CD). This article proposes three broad CD variants based on both distinctive histopathology and clinical behaviour. The pivotal roles of infection with human herpesvirus 8 and interleukin-6 production in the development of CD are emphasized. Finally, the natural history of CD and the myriad of therapeutic options are reviewed in the context of a unified model of CD pathophysiology, and continued areas of uncertainty are discussed.

show abstract

Section: Unicentric Hyaline Vascular Variant (U‐hvv)mentioning

confidence: 99%

The aetiology and management of Castleman disease at 50 years: translating pathophysiology to patient care

2005

View full text Add to dashboard Cite

show abstract

“…65 There are systemic lymph node disorders that have been shown to be 18 F-FDG avid. These include Castleman's disease, 66 also known as angiofollicular or giant lymph node hyperplasia, or Rosai-Dorfman disease, a rare condition of unknown etiology. Rosai-Dorfman disease is characterized by massive, painless, lymphadenopathy with or without a low-grade fever.…”

Section: Genitourinary Tract (Table 5)mentioning

confidence: 99%

Increased 18F-Fluorodeoxyglucose Uptake in Benign, Nonphysiologic Lesions Found on Whole-Body Positron Emission Tomography/Computed Tomography (PET/CT): Accumulated Data From Four Years of Experience With PET/CT

Metser

Even-Sapir

2007

Seminars in Nuclear Medicine

191

118

View full text Add to dashboard Cite

“…However, few reports exist in the literature that demonstrate the 18 F-FDG PET imaging appearance of Castleman disease, and one of these reports demonstrates an amount of radiotracer uptake that overlaps with the range of uptake typical for neoplastic disease. 7,8 Surgical resection is generally implemented as standard treatment of unicentric Castleman disease, with a cure rate approaching 100%. 2,9 Preoperative arterial embolization may be used as an adjunct to surgery to minimize potential excessive blood loss related to lesion hypervascularity.…”

Section: Discussionmentioning

confidence: 99%