Diffuse peritoneal and omental infiltration of prostate cancer detected by 18 F-PSMA-1007 PET/CT was rarely reported. We report a case of an 80-year-old man who was suspected of prostate carcinoma metastasis and underwent 18 F-PSMA-1007 PET/CT for restaging the disease. PET/CT imaging presented intense tracer uptake in the prostate gland, multiple lymph nodes, and bones. Interestingly, we found extremely increased radioactive uptake of diffuse peritoneum and omentum on 18 F-PSMA-1007 PET/CT images, which are very rare metastatic sites for prostate cancer.