FC6.3 Continuous EEG monitoring during thrombolysis in acute hemispheric stroke patients using the brain symmetry index

EEG in ischaemic stroke: Quantitative EEG can uniquely inform (sub-)acute prognoses and clinical management

“…Reporting these outcomes is currently in progress. In serial EEG from 16 tPA recipients a significant correlation was reported between changes in the BSI, and NIHSS changes (de Vos et al, 2008). These changes were generally reported over approximately several hours, in one case over less than an hour.…”

“…Such algorithms are implemented into numerous EEG analysis software packages, and can be informed either by appropriately-positioned electro-oculogram (EOG) electrodes or alternatively, electrodes FP1 and FP2 of the international 10-20 system. In addition, in a study monitoring acute hemispheric IS patients during thrombolysis, the BSI was based on a montage of four bipolar channels per hemisphere (F3-C3, C3-P3, P3-O1, T5-O1, F4-C4, C4-P4, P4-O2, T6-O2; de Vos et al, 2008). In order to minimise possible contamination of BSI measures by potential artefacts associated with eye blinks or movements and electromyogram (EMG) from temporal muscles, frontopolar and temporal electrodes were not included in this montage.…”

“…Across the studies reviewed herein there has been substantial variability in the time of EEG (poststroke onset; see Table 1). Some studies have acquired EEG within several hours (e.g., Finnigan et al, 2004Finnigan et al, , 2006de Vos et al, 2008), some at several or more days post-stroke and others, at one or an-other time across this range within the same sample (e.g., Cuspineda et al, 2003;Sheorajpanday et al, 2011a). Clearly, EEG monitoring during thrombolysis must by definition occur within several hours of stroke onset.…”

Behavioral measures and EEG monitoring using the Brain Symmetry Index during the Wada test in children

“…The BSI has been previously used for real-time quantification of lateralized slowing during thrombolytic therapy in acute ischemic stroke [25]. It has also been used for online quantification of EEG slowing during carotid endarterectomy in 20 patients [26] after an objective BSI criterion for selective shunting was established in a retrospective series of 57 patients [7].…”