Fbxo45 facilitates the malignant progression of breast cancer by targeting Bim for ubiquitination and degradation
Mengmeng Zheng,
Linfeng Wu,
Rongyao Xiao
et al.
Abstract:Background
Breast cancer is one of the common malignancies in women. Evidence has demonstrated that FBXO45 plays a pivotal role in oncogenesis and progression. However, the role of FBXO45 in breast tumorigenesis remains elusive. Exploration of the regulatory mechanisms of FBXO45 in breast cancer development is pivotal for potential therapeutic interventions in patients with breast cancer.
Methods
Hence, we used numerous approaches to explore the fu… Show more
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