Favorable prognosis of patients with prosthetic valve endocarditis caused by gram-negative bacilli of the HACEK group

Meyer, Dale J.; Gerding, Dale N.

doi:10.1016/0002-9343(88)90512-8

Cited by 31 publications

(9 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In two patients, vegetations were visible on the TEE but not on the TTE [29,49]. The size of the vegetations, as determined by echocardiography, was described in only four cases: large (n=2), small (n=1), and <1 cm (n=1) [11,24,30,32]. Destruction of chordae tendinae was noted in two patients and paravalvular abscess and possible annular abscess in two other patients.…”

Section: Diagnosismentioning

confidence: 99%

“…[47] AV Yes PEN + GEN 10 days, then AMP + TOB 41 days Yes [16] AV Yes AMP 4 weeks Yes [41] MV No AMP, then PEN 6 weeks Yes [36] MV No PEN 6 weeks Yes [8] NR NR NR No [19] MV No AMP + GEN 3 weeks, then AMP 3 weeks Yes [30] MV Yes VAN/GEN, then AMP 6 weeks Yes [3] AV Yes PEN/GEN, then CEF 6 weeks Yes [42] MV/AV Yes AMP + GEN, then AMP 9 weeks Yes [29] MV/AV No AMP + GEN 6 weeks Yes [25] AV No CEF 3 weeks Yes [48] AV No CEF + GEN, then CEF 6 weeks Yes [11] AV Yes CEF + GEM 18 days, then AMX 10 weeks Yes [4] MV No CEF 6 weeks Yes [5] AV Comparison of biochemical characteristics of C. hominis and other HACEK organisms…”

Section: Ref Valve Surgery Treatment Curementioning

confidence: 99%

See 1 more Smart Citation

Cardiobacterium hominis endocarditis: two cases and a review of the literature

Malani

Aronoff

Bradley

et al. 2006

Eur J Clin Microbiol Infect Dis

View full text Add to dashboard Cite

Cardiobacterium hominis, a member of the HACEK group (Haemophilus parainfluenzae, Haemophilus aphrophilus, and Haemophilus paraphrophilus, Actinobacillus actinomycetemcomitans, C. hominis, Eikenella corrodens, and Kingella species), is a rare cause of endocarditis. There are 61 reported cases of C. hominis infective endocarditis in the English-language literature, 15 of which involved prosthetic valve endocarditis. There is one reported case of C. hominis after upper endoscopy and none reported after colonoscopy. Presented here are two cases of C. hominis prosthetic valve endocarditis following colonoscopy and a review of the microbiological and clinical features of C. hominis endocarditis. Patients with C. hominis infection have a long duration of symptoms preceding diagnosis (138+/-128 days). The most common symptoms were fever (74%), fatigue/malaise (53%), weight loss/anorexia (40%), night sweats (24%), and arthralgia/myalgia (21%). The most common risk factors were pre-existing cardiac disease (61%), the presence of a prosthetic valve (28%), and history of rheumatic fever (20%). Of the 61 cases reviewed here, the aortic valve was infected in 24 (39%) and the mitral valve in 19 (31%) patients. The average duration of blood culture incubation before growth was detected was 6.3 days (range, 2-21 days). Complications were congestive heart failure (40%), central nervous system (CNS) emboli (21%), arrhythmia (16%), and mycotic aneurysm (9%). C. hominis is almost always susceptible to beta-lactam antibiotics. Ceftriaxone is recommended by the recently published American Heart Association guidelines. The prognosis of C. hominis native valve and prosthetic valve endocarditis is favorable. The cure rate among 60 patients reviewed was 93% (56/60). For prosthetic valve endocarditis, the cure rate was 16/17 (94%). Valve replacement was required in 27 (45%) cases.

show abstract

Section: Diagnosismentioning

confidence: 99%

Section: Ref Valve Surgery Treatment Curementioning

confidence: 99%

Cardiobacterium hominis endocarditis: two cases and a review of the literature

Malani

Aronoff

Bradley

et al. 2006

Eur J Clin Microbiol Infect Dis

View full text Add to dashboard Cite

show abstract

“…Although extremely uncommon, H. parainfluenzae SBE has rarely been cured with antibiotic therapy alone without valve replacement. [18][19][20] …”

Section: Discussionmentioning

confidence: 99%

Haemophilus parainfluenzae mitral prosthetic valve endocarditis in an intravenous drug abuser

2005

View full text Add to dashboard Cite

“…A structural heart disease known before IE onset is a common finding in these patients. Both native and prosthetic heart structures may be involved in this insidious form of IE [17,18].…”

Section: Hacekmentioning

confidence: 99%

Management of Gram-negative and fungal endocarditis

Durante‐Mangoni

Tripodi

Albisinni

et al. 2010

International Journal of Antimicrobial Agents

View full text Add to dashboard Cite

Infective endocarditis is infrequently caused by Gram-negative bacteria or fungi.Gram-negative organisms are responsible for <4% of cases, while fungal endocarditis accounts for <1.5% of culture-positive cases worldwide. Endocarditis due to Gram-negative organisms or fungi is a rare but severe disease. It often has a nosocomial origin, is caused by virulent and often resistant organisms and presents a high rate of complications and high mortality. In this article we present the most recent literature data and address the current management of Gram-negative and fungal infective endocarditis. We also discuss the major challenges of antimicrobial treatment and discuss some issues related to surgical decision-making in difficult-tomanage cases. We finally present our centre's experience with Gram-negative infective endocarditis, with a special focus on the demanding issues that the management of these complex and severely ill patients raise.

show abstract

Favorable prognosis of patients with prosthetic valve endocarditis caused by gram-negative bacilli of the HACEK group

Cited by 31 publications

References 15 publications

Cardiobacterium hominis endocarditis: two cases and a review of the literature

Cardiobacterium hominis endocarditis: two cases and a review of the literature

Haemophilus parainfluenzae mitral prosthetic valve endocarditis in an intravenous drug abuser

Management of Gram-negative and fungal endocarditis

Contact Info

Product

Resources

About