The article presents the results of a comprehensive study of the conditions for the development and spread of natural and technogenic suffusion by the Belarus territory. It is noted that in insignificantly disturbed natural geoenvironment, the most favorable conditions for the development of suffusion have developed within the moraine and water-glacial plains and lowlands of the eastern part of the country, as well as marginal ice ridges and uplands with a cover of loess and loess-like formations with increased silt content, relatively low density of the soil skeleton, easy soakability and thixotropy, which contribute to the intensive development of the suffusion process. Active natural factors, conditions for the development and spread of suffusion, as well as forms of its manifestation in loess and loess-like soil massifs are considered. Suffusion manifestation in technogenically disturbed geoenvironment is analyzed, and its negative impact on functioning of natural-anthropogenic systems of various organization levels is shown by specific examples. In the authors’ opinion, the creation of a monitoring system for the development of suffusion, as well as other exogenous geological and engineering geological processes, will provide up-to-date information on the distribution and manifestation activity of these processes and the factors that determine them.