Fault Diagnosis of the Tooth Belt Transmission of Cartesian Robot

Autsou, Siarhei; Vaimann, Toomas; Rassõlkin, Anton; Kudelina, Karolina; Hyunh, Van Khang

doi:10.1109/iwed54598.2022.9722578

Cited by 4 publications

(1 citation statement)

References 15 publications

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“…It gets its name from the reference system introduced by the philosopher and mathematician Descartes using the coordinate method to highlight its movements along orthogonal axes. Its special distinction point is that it has only prismatic (linear) joints for principal movements; it can therefore move only in a straight line on the three axes [ 35 , 36 ].…”

Section: Roboticsmentioning

confidence: 99%

Robotics and Aseptic Processing in View of Regulatory Requirements

Tanzini,

Ruggeri,

Bianchi

et al. 2023

Pharmaceutics

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Several nanomedicine based medicinal products recently reached the market thanks to the drive of the COVID-19 pandemic. These products are characterized by criticality in scalability and reproducibility of the batches, and the manufacturing processes are now being pushed towards continuous production to face these challenges. Although the pharmaceutical industry, because of its deep regulation, is characterized by slow adoption of new technologies, recently, the European Medicines Agency (EMA) took the lead in pushing for process improvements using technologies already established in other manufacturing sectors. Foremost among these technologies, robotics is a technological driver, and its implementation in the pharma field should cause a big change, probably within the next 5 years. This paper aims at describing the regulation changes mainly in aseptic manufacturing and the use of robotics in the pharmaceutical environment to fulfill GMP (good manufacturing practice). Special attention is therefore paid at first to the regulatory aspect, explaining the reasons behind the current changes, and then to the use of robotics that will characterize the future of manufacturing especially in aseptic environments, moving from a clear overview of robotics to the use of automated systems to design more efficient processes, with reduced risk of contamination. This review should clarify the regulation and technological scenario and provide pharmaceutical technologists with basic knowledge in robotics and automation, as well as engineers with regulatory knowledge to define a common background and language, and enable the cultural shift of the pharmaceutical industry.

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Section: Roboticsmentioning

confidence: 99%