Fatty Foods and Obesity

Calorie for Calorie, Dietary Fat Restriction Results in More Body Fat Loss than Carbohydrate Restriction in People with Obesity

“…Unlike the current study, all previous studies altered multiple macronutrients from their baseline values rather than selectively restricting individual macronutrients. Nevertheless, many studies agreed with our data showing greater weight loss with reduced carbohydrate diets (Anderson, 1944; Bell et al, 1969; Bogardus et al, 1981; Bortz et al, 1968; Bortz et al, 1967; Kekwick and Pawan, 1956; Lewis et al, 1977; Olesen and Quaade, 1960; Pilkington et al, 1960; Rabast et al, 1979; Rabast et al, 1981; Werner, 1955; Yang and Van Itallie, 1976). However, several studies did not detect significant differences in weight loss (Fletcher et al, 1961; Golay et al, 1996; Kinsell et al, 1964; Miyashita et al, 2004; Rumpler et al, 1991; Vazquez and Adibi, 1992; Vazquez et al, 1995).…”

“…Previous inpatient controlled-feeding studies have employed isocaloric reduced-energy diets with fixed protein and varying in carbohydrate and fat to investigate differences in weight loss (Anderson, 1944; Bell et al, 1969; Bogardus et al, 1981; Bortz et al, 1968; Bortz et al, 1967; Fletcher et al, 1961; Golay et al, 1996; Kekwick and Pawan, 1956; Kinsell et al, 1964; Lewis et al, 1977; Miyashita et al, 2004; Olesen and Quaade, 1960; Pilkington et al, 1960; Rabast et al, 1979; Rabast et al, 1981; Rumpler et al, 1991; Vazquez and Adibi, 1992; Vazquez et al, 1995; Werner, 1955; Yang and Van Itallie, 1976). Only two of these previous studies investigated more subjects per diet group than the present study (Golay et al, 1996; Rabast et al, 1979).…”

“…However, several studies did not detect significant differences in weight loss (Fletcher et al, 1961; Golay et al, 1996; Kinsell et al, 1964; Miyashita et al, 2004; Rumpler et al, 1991; Vazquez and Adibi, 1992; Vazquez et al, 1995). Often, the greater weight losses with the low carbohydrate diets were attributed to sodium and water imbalances (Anderson, 1944; Bell et al, 1969; Bortz et al, 1968; Bortz et al, 1967; Lewis et al, 1977; Olesen and Quaade, 1960; Pilkington et al, 1960; Werner, 1955; Yang and Van Itallie, 1976). Furthermore, nitrogen balance measurements in several previous studies have suggested greater lean tissue loss with low-carbohydrate diets (Bell et al, 1969; Bortz et al, 1968; Bortz et al, 1967; Vazquez and Adibi, 1992; Vazquez et al, 1995).…”

The Use of Diethylpropion in the Treatment of Obesity

“…The marked initial fall in weight on both inert and anorectic agents has been noted by other investigators (Hampson, Loraine and Strong 1960; Simkin and Wallace 1960). It has been suggested that this is due to initial dehydration on transferring to a low carbohydrate diet (Olsen and Quaade 1960; Passmore, Strong and Ritchie 1958; Pilkington, Gainsborough, Roseneor and Carey 1960), and the effectiveness of an anorectic agent has to be judged by its behaviour subsequently.…”

Maintenance of weight loss in obese subjects.

“…One subject lost 21-5 kg in two weeks. This has frequently been observed and attributed to loss of fluid when carbohydrate intake is reduced, but which can be regained on isocaloric diets when carbohydrate intake is increased (Olesen and Quaade, 1960;Pilkington et al, 1960;Bloom and Azar, 1963).…”