Fatty acid supplements improve hair coat condition in rhesus macaques

Hamel, Amanda F.; Menard, Mark T.; Novak, Melinda A.

doi:10.1111/jmp.12271

Cited by 6 publications

(5 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…1, 4). The reduction in hair loss in mildly alopecic monkeys, following administration of PUFA, might be due to a decrease in alopecia-related inflammation, associated with the varied levels of the anti-inflammatory cytokine IL-10 and the proinflammatory cytokines TNF-α and IL-1β (47). Anti-inflammatory effects of olive oil with respect to protection against hair fall require further examination.…”

Section: Discussionmentioning

confidence: 99%

Effect of olive oil consumption on aging in a senescence-accelerated mice-prone 8 (SAMP8) model

et al. 2019

View full text Add to dashboard Cite

Background : Mediterranean diets have been linked to a reduced risk of cancer, vascular illnesses, Parkinson's and Alzheimer's disease. Olive oil is the primary fat source in the Mediterranean diet ; however, only a few studies have investigated the effect of olive oil on aging. In the present study, we aimed to determine whether consumption of olive oil significantly influences aging and memory in senescence-accelerated mouse-prone 8 (SAMP8). Methods : SAMP8 and senescence-accelerated mouse resistant 1 (SAMR1) mice were fed either 7% soy oil or 1% olive oil and 6% soy oil during a six-month study period. Reduction in memory in passive avoidance learning was examined after two months from the initiation of the experiment. Results : The weight of organs including the liver, kidney, spleen, and fat tissue changed significantly and memory performance was reduced in SAMP8 than in SAMR1 mice. There were no significant differences in SAMP8 and SAMR1 mice; however, blood triglyceride level decreased significantly in SAMP8 mice fed on olive oil. Conclusions : These results suggest that consuming olive oil may not have a protective role in aging and memory recall, but beneficial effects may be related to improvement in lipid metabolism. J. Med. Invest. 66 : 241-247, August, 2019

show abstract

Section: Discussionmentioning

confidence: 99%

Effect of olive oil consumption on aging in a senescence-accelerated mice-prone 8 (SAMP8) model

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Hair condition, tested in a noninvasive manner, was simultaneously rated. It has been documented that hair condition is closely correlated with immune-endocrine imbalance [21–23], increased social stress [22, 23] and malnutrition [24], all of which can accelerate aging-related decreases in health and functioning. Regarding musculoskeletal aging, we selected the iliac muscle mass as the representative muscle to grade aging-related muscle loss.…”

Section: Discussionmentioning

confidence: 99%

Construction of a comprehensive observer-based scale assessing aging-related health and functioning in captive rhesus macaques

Deng

Guan

Xiao

et al. 2019

Aging

View full text Add to dashboard Cite

Aging-related health and functioning are difficult to quantify in humans and nonhuman primates. We constructed an observer-based scale for daily application in assessing the aging-related health and functioning of rhesus macaques. Ten items referring to an aging appearance, musculoskeletal aging and aging-related eating behavior were selected through a panel consensus. The Aging-related Health and Functioning Scale (AHFS) was constructed based on these scored items form 57 healthy rhesus macaques. High reliability of the AHFS was shown based on Cronbach’s alpha coefficient (0.877). The structure of the AHFS was validated by three exploratory factors. The largest factor, whose four components were dietary uptake, iliac muscle mass, hair condition and fragility, and sex, explained 50.5% of the variation in aging-related health and functioning scores. The second factor, involving age, tooth loss and tooth wear, explained 15.5% of the variation. The lowest-ranking factor comprised only facial redness and accounted for 10% of the variation. A hierarchical cluster analysis validated the good applicability of the scale in distinct samples. From these scale-scored results, complicated aging phenomena observed in humans, including the sex-survival paradox and the calorie-related health-survival paradox, were both demonstrated in rhesus macaques. Therefore, the AHFS provides a valuable approach for aging-related research.

show abstract

“…Fatty acid supplementation reduced alopecia in self-grooming rhesus macaques [50]. In addition, topical linoleic acid application was shown to reverse scalp dermatitis, alopecia, and depigmentation of hair in one case report [51].…”

Section: Fatty Acidsmentioning

confidence: 94%

Integrative and Mechanistic Approach to the Hair Growth Cycle and Hair Loss

Natarelli

Gahoonia

Sivamani

2023

JCM

View full text Add to dashboard Cite

The hair cycle is composed of four primary phases: anagen, catagen, telogen, and exogen. Anagen is a highly mitotic phase characterized by the production of a hair shaft from the hair follicle, whereas catagen and telogen describe regression and the resting phase of the follicle, respectively, ultimately resulting in hair shedding. While 9% of hair follicles reside in telogen at any time, a variety of factors promote anagen to telogen transition, including inflammation, hormones, stress, nutritional deficiency, poor sleep quality, and cellular division inhibiting medication. Conversely, increased blood flow, direct stimulation of the hair follicle, and growth factors promote telogen to anagen transition and subsequent hair growth. This review seeks to comprehensively describe the hair cycle, anagen and telogen balance, factors that promote anagen to telogen transition and vice versa, and the clinical utility of a variety of lab testing and evaluations. Ultimately, a variety of factors impact the hair cycle, necessitating a holistic approach to hair loss.

show abstract

Fatty acid supplements improve hair coat condition in rhesus macaques

Cited by 6 publications

References 13 publications

Effect of olive oil consumption on aging in a senescence-accelerated mice-prone 8 (SAMP8) model

Effect of olive oil consumption on aging in a senescence-accelerated mice-prone 8 (SAMP8) model

Construction of a comprehensive observer-based scale assessing aging-related health and functioning in captive rhesus macaques

Integrative and Mechanistic Approach to the Hair Growth Cycle and Hair Loss

Contact Info

Product

Resources

About