Fatty acid profiles, antioxidant compounds and antiradical properties of<i>Pinus halepensis</i>Mill. cones and seeds

Dhibi, Madiha; Mechri, Beligh; Brahmi, Faten; Skhiri, Fathia; Alsaif, Mohammed A.; Hammami, Mohamed

doi:10.1002/jsfa.5535

Cited by 19 publications

(22 citation statements)

References 50 publications

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“…It should be mentioned that the value of TFC for methanolic extracts of seeds and cones extracts (TFC = 17.14, 193.25, respectively) in the current work were much higher than those reported for the same species in literature [13] in which the methanolic extracts of seeds and cones had TFC equal 0.35 and 3.26, respectively. This can be attributed to the differences in climate, soil composition and other conditions in the countries were the plant was grown [22].…”

Section: Determination Of Total Phenolic Content (Tpc)contrasting

confidence: 83%

“…The DPPH radicals inhibition activity of cones and seeds methanolic extracts (EC50 = 0.00148 mg/mL and 0.127 mg/mL, respectively) was significantly better than that for extracts from the same parts obtained in the in the work [13] in which EC50 was 0.474 mg/mL for cones and 2.323 mg/mL for seeds extracts.…”

Section: Determination Of Total Phenolic Content (Tpc)mentioning

confidence: 74%

“…In the last two decades an enormous number of studies were performed in different countries of Mediterranean basin on extracts and essential oils isolated from different parts (seeds, cones and bark) of Aleppo pine. These works focused on the health effects [10,11], chemical composition, particularly the content of polyphenpls, fatty acids, amino acids, minerals, in addition to antioxidant, antibacterial and antifungal activities [12][13][14][15][16][17][18][19][20][21][22].…”

Section: Phytochemical Analysis and Antibacterial Activity Of Extractmentioning

confidence: 99%

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Phytochemical Analysis and Antibacterial Activity of Extracts from Palestinian Aleppo Pine Seeds, Bark and Cones

Salim¹,

Rimawi²,

Shaheen³

et al. 2018

Asian J. Chem.

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Pinus halepensis (Aleppo pine) is one of the most common trees that are known for their medicinal and economic importance in the Mediterranean region. This work aimed to determine the total phenolic, flavonoid and lipid contents, as well as to study the antioxidant and antibacterial activities of extracts obtained from different parts (cones, bark and seeds) of Pinus halepensis trees cultivated in Palestine. Two extraction techniques (maceration and Soxhlet) using thee different solvents (ethanol, 80 % methanol and hexane) were applied. The results showed that among all extracts, methanolic extract of cones had the highest total phenolic content (431.38 mg equivalent gallic acid/g extract) and the best total flavonoid content (193.25 mg catechin equivalent/g extract) and demonstrated the highest antioxidant activity with EC50 of 1.48 µg/mL. The highest total lipid content using hexane as extraction solvent was found for the extract from seeds (30.1 %). The antibacterial activity of the extracts was studied using agar dilution method against Shigella, Escherichia coli and Staphylococcus aureus. Solutions of the obtained extracts with the concentration range of 10-5 to 10-2 g extract/mL in 20 % aqueous DMSO exhibited 15-80 %, 20-80 % and 20-95 % bacterial inhibition of Shigella, Escherichia coli and Staphylococcus aureus, respectively.

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Section: Determination Of Total Phenolic Content (Tpc)contrasting

confidence: 83%

Section: Determination Of Total Phenolic Content (Tpc)mentioning

confidence: 74%

Section: Phytochemical Analysis and Antibacterial Activity Of Extractmentioning

confidence: 99%

See 1 more Smart Citation

Phytochemical Analysis and Antibacterial Activity of Extracts from Palestinian Aleppo Pine Seeds, Bark and Cones

Salim¹,

Rimawi²,

Shaheen³

et al. 2018

Asian J. Chem.

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“…This result is apparently due to the P. halepensis extract being rich in phenolic antioxidants, which decreased oxidative stress and therefore inflammation [21, 56], as well as to the wound-healing effect of C. oestroides extract [28-31]. …”

Section: Discussionmentioning

confidence: 99%

“…Plant products, such as Aloe vera , sweet almond oil, and olive oil, containing bioactive compounds protect the skin from the radiation-induced damage and have been used as excipients or ingredients in several pharmaceutical and cosmetic preparations [8, 15-20]. Pinus halepensis extracts have shown protective and therapeutic skin properties [21-23]. Bark extracts from P. halepensis contain polyphenols, proanthocyanidins, flavonols, and flavonoids; therefore, they may exert therapeutic effects against pain, inflammation, oxidative stress, and cancer.…”

Section: Introductionmentioning

confidence: 99%

Topical Treatment of Skin Injury Inflicted in Mice by X-Ray Irradiation

Meimeti

Kafanas²,

Pavlou

et al. 2018

Skin Pharmacol Physiol

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Background/Aims: There is no treatment, without side effects, efficiently preventing or curing skin burns, caused by radiotherapy. A new experimental topical treatment protocol was assessed in mice receiving orthovoltage X-rays at an equivalent dose to that applied to human breast cancer patients in conventional radiotherapy. Methods: SKH-HR2 female hairless mice were irradiated on their dorsum with a total dose of 4,300 cGy during a 1-month period (20 fractions). The treatment group received a combination of 3 topical products, an oil-in-water cream, a gel containing Pinus halepensis bark aqueous extract, and an ointment containing olive oil extract of the marine isopod Ceratothoa oestroides. The positive control group was treated with a conventionally used commercial gel, whereas the negative control group did not receive any topical treatment. Skin alterations were evaluated by macroscopic examinations, measurements of transepidermal water loss (TEWL), melanin content, erythema intensity, hydration, and histopathology assessment. Results: Sixty days after radiation, TEWL and hydration values were abnormal and elements of acute, chronic, and granulomatous inflammation were present in all cases. The severest damage was detected in the deeper dermis. Treatment showed a comparatively beneficial effect on chronic and granulomatous inflammation while positive control was beneficial on acute inflammation. Conclusion: Skin anti-inflammatory treatment was the most effective but must be applied for several months. Further preclinical studies should be conducted, assimilating a human cancer radiation therapeutic schema with the aim of optimizing skin inflammation treatment.

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Morphological and Chemical Differentiation between Tunisian Populations of Pinus halepensis, Pinus brutia, and Pinus pinaster

Khouja

Alves

Melo

et al. 2021

Chemistry & Biodiversity

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The lipid fraction of seeds from different pine species and populations was studied regarding total lipid content, fatty acid profile and vitamin E composition. The investigated seeds contained a high percentage of lipid (13.6 to 31.5 %). Lipid fractions were found to be rich in vitamin E, which varied significantly among species and populations. P. halepensis (Ph−Hn) showed the highest content of vitamin E (256.3 mg/kg of seeds) and the uppermost content of α‐tocopherol (44 mg/kg). However, P. halepensis (Ph−Kas) was the richest in γ‐tocopherol (204.9 mg/kg). Lipid fractions had a low content of δ‐tocopherol (1.2 to 3.6 mg/kg. The highest content of γ‐tocotrienol (∼18 %) was determined for P. halepensis (Ph−Dc and Ph−Hn). Thirteen fatty acids were identified by GC‐FID with significant variation between the investigated species. The linoleic acid was the major fatty acid followed by oleic acid and palmitic acid. The chemical differentiation among species for the composition of fatty acids and vitamin E was confirmed by PCA. Significant correlations were observed between the content of vitamin E and fatty acids and ecological parameters of P. halepensis populations.

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Fatty acid profiles, antioxidant compounds and antiradical properties ofPinus halepensisMill. cones and seeds

Cited by 19 publications

References 50 publications

Phytochemical Analysis and Antibacterial Activity of Extracts from Palestinian Aleppo Pine Seeds, Bark and Cones

Phytochemical Analysis and Antibacterial Activity of Extracts from Palestinian Aleppo Pine Seeds, Bark and Cones

Topical Treatment of Skin Injury Inflicted in Mice by X-Ray Irradiation

Morphological and Chemical Differentiation between Tunisian Populations of Pinus halepensis, Pinus brutia, and Pinus pinaster

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