Fatty Acid Composition of Lamb Liver, Muscle, And Adipose Tissues in Response to Rumen-Protected Conjugated Linoleic Acid (CLA) Supplementation Is Tissue Dependent

Abstract

The tissue-specific response to rumen-protected conjugated linoleic acid supply (rpCLA) of liver, two muscles, and three adipose tissues of heavy lambs was studied. Twenty-four lambs, 8 months old, divided into 4 groups of 6, were fed at libitum on a ration supplemented without or with a mixture of rpCLA. Silica and hydrogenated soybean oil was the rpCLA coating matrix. The lambs were slaughtered at 11 months of age. Tissues were collected and analyzed for their FA profiles. The dietary rpCLA supplement had no influence on carcass fatness nor on the fat content of the liver and tissues and had little influence on the FA profiles of these tissues. In the adipose tissues, rpCLA increased the proportions of saturated FAs, 18:0 and 18:2t10c12, and decreased the proportions of monounsaturated FAs in the adipose tissues. In muscles, the effects were the opposite. The results suggest that Δ9 desaturase activity is inhibited by the rpCLA mixture in adipose tissues to a greater extent than in the other tissues.

Dose response of rumen‐protected conjugated linoleic acid supplementation to fattening bulls and heifers on growth, and carcass and meat quality

“…In the current study, we observed a tendency towards a non-linear alteration in liver weight in response to long-term administration of rpCLA, signalling the importance of monitoring the health of the liver under CLA supplementation. However, in a previous research we found no effects of CLA administration on liver weight in growing lambs (Schiavon et al, 2017), while in another study we found an association between rpCLA administration and a marked reduction in the number of bulls with swollen legs (Schiavon et al, 2010), which might reflect a positive effect of CLA on the immune system, as previously proposed by Pariza et al, (2001). Park et al, (1997) and Pariza et al, (2001) noted that reductions in body fat in model animals appeared to be mainly due to lower body fat accretion induced by CLA.…”

“…In lambs, the response was found to be tissue-dependent (Schiavon, Bergamaschi, Pellattiero, Simonetto, & Tagliapietra, 2017). A number of studies (reviewed by Kim, Kim, Whang, & Park, 2016) have also shown that CLA increases lean body mass, body protein and specific skeletal muscle mass.…”

“…Mixtures of conjugated linoleic acids have been found to reduce body fat in mice, rats, hamsters, pigs and humans (Patureau‐Mirand et al, ), an effect that is mainly related to alterations in lipid metabolism induced by the 18:2 t 10, c 12 isomer (Pariza et al, ). In lambs, the response was found to be tissue‐dependent (Schiavon, Bergamaschi, Pellattiero, Simonetto, & Tagliapietra, ). A number of studies (reviewed by Kim, Kim, Whang, & Park, ) have also shown that CLA increases lean body mass, body protein and specific skeletal muscle mass.…”

Influence of dietary protein content on the chemico-physical profile of dry-cured hams produced by pigs of two breeds

“…In line with the experimental design, the effects of BR, diet, sex and BR × diet were tested using ham within the BR × diet × sex interaction as the error line, whereas the effects of tissue and its interactions were tested on the random residual, according to model used in Schiavon et al . 48 .…”

Comprehensive Evaluation of Parameters Affecting One-Step Method for Quantitative Analysis of Fatty Acids in Meat

“…Meat FA composition is affected by breed [6], and age [7] and can also be altered during animal production by making changes to the diets offered to the animals [8,9,10]. Overall, the target of such changes is to reduce the concentrations of saturated fatty acids (SFA) and increase those of polyunsaturated fatty acids (PUFA) [11].…”