Fatigue of Biomaterials and Biomedical Systems

Klenam, Desmond; Soboyejo, Winston O.

doi:10.1016/b978-0-12-822944-6.00045-1

Cited by 2 publications

(2 citation statements)

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“…Biomaterials are widely used in dentistry and orthopedics 1–3 . The properties of biomaterials for dental and orthopedics must satisfy some material requirements to be successful in their specific application.…”

Section: Introductionmentioning

confidence: 99%

“…Biomaterials are widely used in dentistry and orthopedics. [1][2][3] The properties of biomaterials for dental and orthopedics must satisfy some material requirements to be successful in their specific application. Hydroxyapatite (HA), a pure calcium phosphate (CaP), is a preferred biomaterial for dental and orthopedic applications [4][5][6] due to its chemical and crystal structure similarities to human skeletal apatite.…”

Section: Introductionmentioning

confidence: 99%

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Hydroxyapatite nano‐pillars on TI‐6Al‐4V: Enhancements in cell spreading and proliferation during cell/surface integration

Osafo,

Etinosa,

Obayemi

et al. 2024

J Biomedical Materials Res

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Despite the attractive combinations of cell/surface interactions, biocompatibility, and good mechanical properties of Ti‐6Al‐4V, there is still a need to enhance the early stages of cell/surface integration that are associated with the implantation of biomedical devices into the human body. This paper presents a novel, easy and reproducible method of nanoscale and nanostructured hydroxyapatite (HA) coatings on Ti‐6Al‐4V. The resulting nanoscale coatings/nanostructures are characterized using a combination of Raman spectroscopy, scanning electron microscopy equipped with energy dispersive x‐ray spectroscopy. The nanostructured/nanoscale coatings are shown to enhance the early stages of cell spreading and integration of bone cells (hFOB cells) on Ti‐6Al‐4V surfaces. The improvements include the acceleration of extra‐cellular matrix, cell spreading and proliferation by nanoscale HA structures on the coated surfaces. The implications of the results are discussed for the development of HA nanostructures for the improved osseointegration of Ti‐6Al‐4V in orthopedic and dental applications.

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Section: Introductionmentioning

confidence: 99%