Fatigue in ankylosing spondylitis

Missaoui, B.; Revel, Michel

doi:10.1016/j.annrmp.2006.03.008

Cited by 28 publications

(28 citation statements)

References 14 publications

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“…Fatigue has been highlighted in external studies as a major symptom associated with AS, with high disease activity predicting high levels of fatigue [ 53 ]. Further studies also support the hypothesis that fatigue is negatively influenced by sleep disorders, associated with poor sleep quality and interrupted sleep for patients with spondyloarthritis (SpA) [ 54,55 ]. It has also been proposed that sleep deprivation or chronic insomnia may cause shifts in cytokine secretion which then mediate inflammation and play a role in the experience of daytime fatigue [ 56,57 ].…”

Section: Fatiguementioning

confidence: 83%

Prevalence and factors associated with disturbed sleep in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a systematic review

et al. 2016

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Section: Fatiguementioning

confidence: 83%

Prevalence and factors associated with disturbed sleep in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a systematic review

et al. 2016

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“…Fatigue represents the third most common complaint after pain and stiffness, the major symptoms of AS [3]. In some studies, fatigue was reported as the main symptom by 50-65% of patients [20,21].…”

Section: Discussionmentioning

confidence: 99%

“…In ankylosing spondylitis AS disease, fatigue has been only recently considered a core symptom greatly affecting patients [1,3].…”

Section: Introductionmentioning

confidence: 99%

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Fatigue in patients with ankylosing spondylitis: prevalence and relationships with disease-specific variables, psychological status, and sleep disturbance

et al. 2011

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This study aims to evaluate the frequency of fatigue in Moroccan patients with ankylosing spondylitis (AS), and its relationships with disease-specific variables, psychological status, and sleep disturbance. A cross-sectional study included patients fulfilled the modified New York classification criteria for ankylosing spondylitis. To assess fatigue, the first item of Bath ankylosing spondylitis disease activity index (BASDAI) and the multidimensional assessment of fatigue (MAF) was used. The evaluation included the activity of the disease (BASDAI), global well-being (Bath ankylosing spondylitis global index), functional status (Bath ankylosing spondylitis functional index), metrologic measurements (Bath ankylosing spondylitis metrological index), and visual analog scale of axial or joint pain. The erythrocyte sedimentation rate and C-reactive protein were measured. To assess psychological status, the hospital anxiety and depression scale (HADS) was used. Sleep disturbance was assessed by the fourth item of Hamilton anxiety scale. One hundred and ten patients were included, of average age 38.0 years ± 12.6. In our data, 66.4% experienced severe fatigue (BASDAI fatigue ≥ 5). The mean total score of MAF was 26 ± 12.77. The disease-specific variables contributed significantly with both BASDAI fatigue and MAF as dependent variables, accounting for 71.3 and 65.6% of the variance, respectively. The contribution of the depression, anxiety, and sleep disturbance were 24.9, 18.4 and 15.4%, respectively. This study state the importance of fatigue in AS patients. Even though disease activity was the most powerful predictor of fatigue, the effects of psychogenic factors and sleep disturbance, should be taken into consideration in the management of AS.

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“…The pain can be unilateral or intermittent, later becomes persistent or bilateral and the lumbar area becomes stiff and painful [3,8]. Fatigue can frequently appear related to pain and stiffness [9].…”

Section: Introductionmentioning

confidence: 99%

Improvement in pain intensity, spine stiffness, and mobility during a controlled individualized physiotherapy program in ankylosing spondylitis

et al. 2011

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Fatigue in ankylosing spondylitis

Cited by 28 publications

References 14 publications

Prevalence and factors associated with disturbed sleep in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a systematic review

Prevalence and factors associated with disturbed sleep in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a systematic review

Fatigue in patients with ankylosing spondylitis: prevalence and relationships with disease-specific variables, psychological status, and sleep disturbance

Improvement in pain intensity, spine stiffness, and mobility during a controlled individualized physiotherapy program in ankylosing spondylitis

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