Fatigue in advanced cancer patients attending an outpatient palliative radiotherapy clinic as screened by the Edmonton Symptom Assessment System

Zeng, Liang; Koo, Kaitlin; Zhang, Liying; Jon, Florencia; Dennis, Kristopher; Holden, Lori; Nguyen, Janet; Tsao, May; Barnes, Elizabeth; Danjoux, Cyril; Sahgal, Arjun; Chow, Edward

doi:10.1007/s00520-011-1179-8

Cited by 29 publications

(15 citation statements)

References 35 publications

(38 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Carey et al reported that terminally ill female cancer patients were less fatigued than their male counterparts [10]. However, Zeng et al found contrasting evidence in a population of advanced cancer patients referred for palliative radiotherapy, in which female patients experienced more fatigue than male patients [13]. Similar findings were seen in the study by Zimmerman et al, in which female patients also had more fatigue than male patients [14].…”

Section: Resultssupporting

confidence: 63%

“…Thirdly, the heterogeneity of the patient population may also explain certain differences in findings. [10,13]. This may contribute to the differences in findings and may also explain other discrepancies between studies as terminally-ill inpatients have a lower performance status on average in comparison to the other advanced cancer patients [4,10,11].…”

Section: Discussioncontrasting

confidence: 45%

“…Both males and females experienced similar frustration and exhaustion, however a significant difference was found between the amounts of helplessness experienced, with females experiencing greater helplessness [12]. Gender differences were also observed in symptoms of fatigue [10,13,14]. Carey et al reported that terminally ill female cancer patients were less fatigued than their male counterparts [10].…”

Section: Resultsmentioning

confidence: 83%

See 2 more Smart Citations

Gender differences in symptoms experienced by advanced cancer patients: a literature review

Wong

Bedard

Pulenzas

et al. 2013

RHC

Self Cite

View full text Add to dashboard Cite

INTRODUCTION: Advanced cancer patients are multi-symptomatic and require attentive palliative care. As gender differences are apparent in multiple aspects of everyday life, this literature review aims to determine the gender differences seen in the population of advanced cancer patients and the symptoms that they experience. METHODS: A literature review was conducted using the OvidSP Medline database from 1946 to November 2012. Randomized, prospective or retrospective cohort studies on advanced cancer patients who were undergoing any type of palliative treatments (palliative radiation, chemotherapy) or those in which palliative treatments have failed (antalgic treatment) were included. The patient population, tools/questionnaire used and gender differences in symptoms found statistically or qualitatively significant in the respective studies were extracted. RESULTS: Of the 163 studies resulting from the literature search, nineteen publications were identified. Gender differences in multiple symptoms were discovered. Gender differences were commonly found in symptoms of emotional changes, fatigue, gastrointestinal symptoms (nausea, vomiting, and diarrhea) anxiety, tension, sleep problems and pain. CONCLUSION: At present, gender differences seen in the symptoms experienced by advanced cancer patients continues to be inconclusive. Further study investigating gender differences in the symptoms experienced by advanced cancer patients as the primary endpoint is recommended.

show abstract

Section: Resultssupporting

confidence: 63%

Section: Discussioncontrasting

confidence: 45%

Section: Resultsmentioning

confidence: 83%

See 1 more Smart Citation

Gender differences in symptoms experienced by advanced cancer patients: a literature review

Wong

Bedard

Pulenzas

et al. 2013

RHC

Self Cite

View full text Add to dashboard Cite

show abstract

“…Moderate fatigue was shown in 66% of advanced stage cancer patients prior to radiotherapy [30]. This high prevalence of fatigue further underscores the importance of exercise therapy combined with palliative radiotherapy, respectively.…”

Section: Discussionmentioning

confidence: 99%

Quality of life and fatigue of patients with spinal bone metastases under combined treatment with resistance training and radiation therapy- a randomized pilot trial

et al. 2014

View full text Add to dashboard Cite

BackgroundThe aim of this trial was to compare the effects of resistance training versus passive physical therapy on quality of life (QoL), fatigue, and emotional distress outcomes during radiation therapy in patients with spinal bone metastases under radiotherapy (RT).MethodsIn this randomized trial, 60 patients were treated from September 2011 until March 2013 into one of the two groups: isometric resistance training or physical therapy with thirty patients in each group during RT. EORTC QLQ-BM22, EORTC QLQ-FA13, and FBK-R10 were assessed at baseline, three months, and six months after RT.ResultsPsychosocial aspects in resistance training group (Arm A) were significantly improved after three (p = 0.001) and six months (p = 0.010). Other rated items of the QLQ-BM22 painful site, and pain characteristics were without significant differences. Functional interference showed a positive trend after six months (p = 0.081). After six months, physical fatigue (p = 0.013), and interference with daily life (p = 0.006) according to the QLQ-FA13 assessment improved in Arm A significantly. Emotional distress was in Arm A lower after six months (p = 0.016). The Cohen’s effect size confirmed the clinically significant improvement of these findings.ConclusionsIn this group of patients we were able to show that guided isometric resistance training of the paravertebral muscles can improve functional capacity, reduce fatigue and thereby enhance QoL over a 6-months period in patients with stable spinal metastases. The results offer a rationale for future large controlled investigations to confirm these findings.Trial registrationClinical trial identifier NCT01409720

show abstract

“…People with cancer often face remarkable pain problems with varying origins, such as the disease itself and its treatment (Chang, Arnold, & Savarese, ; Dawn, ). There are several studies pointing out that one of the most common symptoms in people with cancer is pain (Posternak et al, ; Walsh, Donnelly, & Rybicki, ) and fatigue (Peters, Goedendorp, Verhagen, Van Der Graaf, & Bleijenberg, ; Shao et al, ; Wang et al, ; Zeng et al, ). It is estimated that about 33% of all people with cancer have moderate and severe pain, and for these people, everyday activities and social interactions may be challenging.…”

Section: Introductionmentioning

confidence: 99%

Pain, fatigue, anxiety and depression in older home‐dwelling people with cancer

et al. 2019

View full text Add to dashboard Cite

AimGlobally, cancer incidence counts for more than 14 million cases and the number increases with age. The aim of this study was to investigate the occurrence of pain, fatigue, anxiety and depression in association with demographic and clinical factors.DesignA cross‐sectional descriptive design was used.MethodsWe performed descriptive statistics to analyse the questionnaires completed from 174 older home‐dwelling people with cancer.ResultsThe people with cancer reported low occurrence of pain, fatigue, anxiety and depression. We found strong correlation between anxiety and depression. Women reported significantly higher scores of anxiety and depression than men. A higher pain score was associated with higher scores of fatigue and anxiety.ConclusionsHome care personnel meeting older home‐dwelling people with cancer should emphasize these people’ mental health problems and be aware that pain, fatigue and anxiety may occur at the same time.

show abstract

Fatigue in advanced cancer patients attending an outpatient palliative radiotherapy clinic as screened by the Edmonton Symptom Assessment System

Cited by 29 publications

References 35 publications

Gender differences in symptoms experienced by advanced cancer patients: a literature review

Gender differences in symptoms experienced by advanced cancer patients: a literature review

Quality of life and fatigue of patients with spinal bone metastases under combined treatment with resistance training and radiation therapy- a randomized pilot trial

Pain, fatigue, anxiety and depression in older home‐dwelling people with cancer

Contact Info

Product

Resources

About