Fatigue and fracture of wires and cables for biomedical applications

Gbur, Janet L.; Lewandowski, John J.

doi:10.1080/09506608.2016.1152347

Cited by 26 publications

(11 citation statements)

References 165 publications

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“…CoCr alloys also have one order of magnitude greater corrosion resistance in comparison with SSs. Mainly, due to these properties, cobalt and its alloys specially, MP35N, modified 35NLT and Elgiloy, have achieved wide attention for fabrication of K-wires, cerclage wires and guide wires [86].…”

Section: Chemical Composition Alloy Astm Number Applicationmentioning

confidence: 99%

Biodegradable Metallic Wires in Dental and Orthopedic Applications: A Review

Asgari

Hang

Chang

et al. 2018

Metals

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Abstract:Owing to significant advantages of bioactivity and biodegradability, biodegradable metallic materials such as magnesium, iron, and zinc and their alloys have been widely studied over recent years. Metallic wires with superior tensile strength and proper ductility can be fabricated by a traditional metalworking process (drawing). Drawn biodegradable metallic wires are popular biodegradable materials, which are promising in different clinical applications such as orthopedic fixation, surgical staples, cardiovascular stents, and aneurysm occlusion. This paper presents recent advances associated with the application of biodegradable metallic wires used in dental and orthopedic fields. Furthermore, the effects of some parameters such as the surface modification, alloying elements, and fabrication process affecting the degradation rate as well as biocompatibility, bioactivity, and mechanical stability are reviewed in the most recent works pertaining to these materials. Finally, possible pathways for future studies regarding the production of more efficient biodegradable metallic wires in the regeneration of bone defects are also proposed.

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Section: Chemical Composition Alloy Astm Number Applicationmentioning

confidence: 99%

Biodegradable Metallic Wires in Dental and Orthopedic Applications: A Review

Asgari

Hang

Chang

et al. 2018

Metals

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“…Careful engineering of robust transdermal ports and connectors is usually required to reliably interface external equipment to the implanted device over weeks or months of implantation. Some studies revealed that the bioelectronic system itself does not fail but its interface to the outside does …”

Section: Maturity Of Hybrid Technologiesmentioning

confidence: 99%

Conformable Hybrid Systems for Implantable Bioelectronic Interfaces

2019

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of Things (IoT) to wellness and medical technologies. In the past decade, significant efforts have been deployed to exploit these technologies to design and manufacture conformable bioelectronic interfaces.Mechanical compliance is a critical specification for the long-term integration of on-skin devices and implants with a biological host. The latter is largely composed of soft tissues, with Young's moduli E in the range from 100 Pa to 10 MPa (excluding bones and cartilage), [1] and sustains different physiological dynamic behaviors, e.g., repeated displacements of hundreds of micrometers at 1 Hz in the heart or brain, [2] volumetric changes up to 8% in the heart, [3] or large flexion and angular displacement in the skin or spinal cord. [4] In contrast, electronic materials are stiff, with the elastic modulus in the range of 1 GPa (organic materials) to 100 GPa (inorganic materials) and rigid, bearing little strain without displaying mechanical failure or defect generation. Interfaces between such disparate biological and man-made materials suffer therefore from a mechanical mismatch that hinders reliable and continued device function in the body. [1,5] Several approaches have been used to engineer mechanical compliance within an electronic device or circuit. [6] Outcomes of such conformable circuits include improved mitigation of foreign body reaction (FBR) in vivo compared to rigid interfaces, [7] access to so far unreachable regions, [8] and bidirectional communication with high spatiotemporal resolution with the biological host.Monolithic integration of electronic devices and circuits on semiconductor wafers offers extreme miniaturization and very high device density (e.g., >10 8 transistors mm −2 , Intel FinFET Technology nodes [9] ). Such large scale of integration cannot be achieved for electronics prepared on conformable carrier substrates, as this class of devices employs lower performance device materials and polymeric substrates with low chemical and/or thermal stability leading to limited lithographic resolution and large transistor sizes. These constraints typically worsen as the compliance of the substrate increases. Some of the highest device densities reported to date are >10 000 cm −2 on flexible substrate [10] and 347 cm −2 on stretchable carrier. [11] Conformable hybrid systems leverage the performance of standard complementary metal-oxide-semiconductor integrated circuits (ICs) and the compliance of discrete flexible or stretchable components and carriers, to effectively provide high-performance and mechanically compliant electronic circuits. They call for new Conformable bioelectronic systems are promising tools that may aid the understanding of diseases, alleviate pathological symptoms such as chronic pain, heart arrhythmia, and dysfunctions, and assist in reversing conditions such as deafness, blindness, and paralysis. Combining reduced invasiveness with advanced electronic functions, hybrid bioelectronic systems have evolved tremendously in the last decade, pushed by progress in materials ...

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“…This may lead to additional residual stresses in the stent, which may affect its deployment once inserted into the body, and may also affect its fatigue endurance when subjected to pulsatile physiological loads. A recent review has also shown significant scatter in the fatigue performance of nitinol wires [ 246 ].…”

Section: Cardiovascular Stents and Their Required Mechanical Propementioning

confidence: 99%

A Critical Review on Metallic Glasses as Structural Materials for Cardiovascular Stent Applications

Jafary-Zadeh

Kumar

Branı́cio

et al. 2018

JFB

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Functional and mechanical properties of novel biomaterials must be carefully evaluated to guarantee long-term biocompatibility and structural integrity of implantable medical devices. Owing to the combination of metallic bonding and amorphous structure, metallic glasses (MGs) exhibit extraordinary properties superior to conventional crystalline metallic alloys, placing them at the frontier of biomaterials research. MGs have potential to improve corrosion resistance, biocompatibility, strength, and longevity of biomedical implants, and hence are promising materials for cardiovascular stent applications. Nevertheless, while functional properties and biocompatibility of MGs have been widely investigated and validated, a solid understanding of their mechanical performance during different stages in stent applications is still scarce. In this review, we provide a brief, yet comprehensive account on the general aspects of MGs regarding their formation, processing, structure, mechanical, and chemical properties. More specifically, we focus on the additive manufacturing (AM) of MGs, their outstanding high strength and resilience, and their fatigue properties. The interconnection between processing, structure and mechanical behaviour of MGs is highlighted. We further review the main categories of cardiovascular stents, the required mechanical properties of each category, and the conventional materials have been using to address these requirements. Then, we bridge between the mechanical requirements of stents, structural properties of MGs, and the corresponding stent design caveats. In particular, we discuss our recent findings on the feasibility of using MGs in self-expandable stents where our results show that a metallic glass based aortic stent can be crimped without mechanical failure. We further justify the safe deployment of this stent in human descending aorta. It is our intent with this review to inspire biodevice developers toward the realization of MG-based stents.

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Fatigue and fracture of wires and cables for biomedical applications

Cited by 26 publications

References 165 publications

Biodegradable Metallic Wires in Dental and Orthopedic Applications: A Review

Biodegradable Metallic Wires in Dental and Orthopedic Applications: A Review

Conformable Hybrid Systems for Implantable Bioelectronic Interfaces

A Critical Review on Metallic Glasses as Structural Materials for Cardiovascular Stent Applications

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