Fatigue and acute coronary syndrome: a systematic review of contributing factors

Johnston, Sujit; Eckhardt, Ann L.

doi:10.1016/j.hrtlng.2018.03.005

Cited by 11 publications

(9 citation statements)

References 45 publications

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“…Fatigue has also been identified as a predictor of worsening quality of life in patients newly diagnosed with CAD and in patients with chronic CAD ( 4 ) . This symptom also impairs psychosocial and physiological functionality ( 23 - 24 ) . Other symptoms, such as palpitation, can occur both in the initial stage of the disease, due to arrhythmias related to a recent AMI and in advanced stages of chronic CAD, due to increased areas of ischemia and consequent fibrosis ( 3 ) .…”

Section: Discussionmentioning

confidence: 99%

Prevalence of pharmacological adherence in patients with coronary artery disease and associated factors

Padilha

Santos

Lopes

et al. 2021

Rev. Latino-Am. Enfermagem

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Objective: to assess the prevalence of pharmacological adherence in patients with coronary artery disease and to identify factors associated with adherence. Method: a crosssectional, correlational study, including 198 patients with a previous diagnosis of coronary artery disease. Pharmacological adherence was assessed by the four-item Morisky Green test, and the factors that potentially interfere with adherence were considered independent variables. The association between the variables was determined by the Cox model, with a 5% significance level. Results: 43% of the patients adhered to the treatment. Fatigue and palpitation, never having consumed alcohol and being served by medical insurance were associated with adherence. Lack of adherence was associated with considering the treatment complex, consumption of alcohol and being served by the public health care system. In the multiple analysis, the patients with fatigue and palpitations had a prevalence of adherence around three times higher and alcohol consumption was associated with a 2.88 times greater chance of non-adherence. Conclusion: more than half of the patients were classified as non-adherent. Interventions can be directed to some factors associated with lack of adherence.

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Section: Discussionmentioning

confidence: 99%

Prevalence of pharmacological adherence in patients with coronary artery disease and associated factors

Padilha

Santos

Lopes

et al. 2021

Rev. Latino-Am. Enfermagem

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“…Many factors affect the occurrence and development of ACS, such as gender, fatigue, and frailty [31][32][33]. According to "China cardiovascular disease report 2018," the mortality rate of AMI showed an overall upward trend from 2002 to 2016, and the mortality rate in rural areas was higher than that in urban areas many times.…”

Section: Discussionmentioning

confidence: 99%

Biodata Mining of Differentially Expressed Genes between Acute Myocardial Infarction and Unstable Angina Based on Integrated Bioinformatics

Guo

Huang

Liu

et al. 2021

BioMed Research International

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Acute coronary syndrome (ACS) is a complex syndrome of clinical symptoms. In order to accurately diagnose the type of disease in ACS patients, this study is aimed at exploring the differentially expressed genes (DEGs) and biological pathways between acute myocardial infarction (AMI) and unstable angina (UA). The GSE29111 and GSE60993 datasets containing microarray data from AMI and UA patients were downloaded from the Gene Expression Omnibus (GEO) database. DEG analysis of these 2 datasets is performed using the “limma” package in R software. DEGs were also analyzed using protein-protein interaction (PPI), Molecular Complex Detection (MCODE) algorithm, Gene Ontology (GO), and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis. Correlation analysis and “cytoHubba” were used to analyze the hub genes. A total of 286 DEGs were obtained from GSE29111 and GSE60993, including 132 upregulated genes and 154 downregulated genes. Subsequent comprehensive analysis identified 20 key genes that may be related to the occurrence and development of AMI and UA and were involved in the inflammatory response, interaction of neuroactive ligand-receptor, calcium signaling pathway, inflammatory mediator regulation of TRP channels, viral protein interaction with cytokine and cytokine receptor, human cytomegalovirus infection, and cytokine-cytokine receptor interaction pathway. The integrated bioinformatical analysis could improve our understanding of DEGs between AMI and UA. The results of this study might provide a new perspective and reference for the early diagnosis and treatment of ACS.

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“…19 Conversely, the presentation of left anterior chest pain and pleuritic pain were less associated with ACS in AA women. 19,20 AA women notably experience a higher symptom burden and report more symptoms after an ACS event compared with White women. 11,19,20 Moreover, AAs presenting with fatigue are highly likely to be diagnosed with ACS.…”

Section: Presentationmentioning

confidence: 98%

Examining Acute Coronary Syndrome Across Ethnicity, Sex, and Age

Leon¹,

Winokur²

2022

The Journal for Nurse Practitioners

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Fatigue and acute coronary syndrome: a systematic review of contributing factors

Cited by 11 publications

References 45 publications

Prevalence of pharmacological adherence in patients with coronary artery disease and associated factors

Prevalence of pharmacological adherence in patients with coronary artery disease and associated factors

Biodata Mining of Differentially Expressed Genes between Acute Myocardial Infarction and Unstable Angina Based on Integrated Bioinformatics

Examining Acute Coronary Syndrome Across Ethnicity, Sex, and Age

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