Fate of antibiotics and antibiotic resistance genes in home water purification systems

Gu, Xinchen; Zhai, Hongchen; Cheng, Shengzi

doi:10.1016/j.watres.2020.116762

Cited by 45 publications

(7 citation statements)

References 37 publications

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“…However, only microdose of antibiotics can be absorbed and metabolized by the human body. 5,6 Various antibiotics and their metabolites enter the water environment through different ways, 7,8 leading to serious damage to the human body and environment. In another way, their overuse may also lead to drug resistance in pathogenic bacteria.…”

Section: ■ Introductionmentioning

confidence: 99%

“…Since the first antibiotic penicillin was discovered in 1928, many antibiotics were widely used in the clinical treatment of microbial and bacterial infections, , aquaculture, , and many others with the development of society. However, only micro-dose of antibiotics can be absorbed and metabolized by the human body. , Various antibiotics and their metabolites enter the water environment through different ways, , leading to serious damage to the human body and environment. In another way, their overuse may also lead to drug resistance in pathogenic bacteria .…”

Section: Introductionmentioning

confidence: 99%

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Detection Enhancement of One Multifunctional Cd-Metal–Organic Framework toward Tetracycline Antibiotics by Simply Mixing Eu³⁺ in Suspension

et al. 2023

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It is necessary to find more simple methods to improve the detection selectivity and sensitivity of antibiotics. Herein, we constructed a novel three-dimensional (3D) Cd-MOF LCU-117 assembled from p-terphenyl-4,2″,5″,4′-tetracarboxylic acid, which showed a special 3D helical structure with carboxylic acid ligands and nitrogen-containing ligands crossing each other vertically. Luminescence measurements indicated that LCU-117 has high selectivity and sensitivity toward Eu3+ through the ratiometric effect. Meanwhile, this complex itself could detect antibiotics oxytetracycline (OTC) through the turn-off mechanism. When Eu3+ was added in suspensions of LCU-117 (noted as Eu3+@LCU-117), the detection toward OTC was enhanced significantly and visually. The sensing mechanism was investigated in detail by various measurements and theoretical calculations. LCU-117 has a good effect on the logic gate, potential fingerprint detection, and mixed-matrix membranes (MMMs). The practical application for monitoring OTC in water samples also provided a satisfactory result.

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Section: ■ Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Detection Enhancement of One Multifunctional Cd-Metal–Organic Framework toward Tetracycline Antibiotics by Simply Mixing Eu³⁺ in Suspension

et al. 2023

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“…Saccharimonadales belongs to Patescibacteria , and its relative abundance is also greatly reduced. Previous studies have shown that Patescibacteria are significantly positively correlated with ARGs [ 41 ]. Saccharimonadales are resistant bacteria to sulfonamide antibiotics [ 42 ].…”

Section: Analysis and Discussionmentioning

confidence: 99%

Removal of Sulfonamide Resistance Genes in Fishery Reclamation Mining Subsidence Area by Zeolite

Yuan

Lin

Cheng

et al. 2022

IJERPH

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A majority of subsidence lakes were reclaimed as fish ponds, but the widespread use of antibiotics has caused the pollution of antibiotic resistance genes (ARGs). This paper uses zeolite as a filter material to construct a horizontal submersible wastewater treatment device and explores its effect on the removal of conventional pollutants and sulfonamide ARGs in wastewater. The results showed that the removal of total nitrogen and ammonia nitrogen by the zeolite filter media were 59.0% and 63.8%, respectively, which were higher than the removal of total phosphorus and COD. The absolute abundances of sul1 and sul2 in wastewater were 2.81 × 104 copies·L−1 and 2.42 × 103 copies·L−1. On average, 60.62% of sul1 and 75.84% of sul2 can be removed, and more than 90% of sul1 and sul2 can be removed. Experiments showed that the residence time of wastewater in the treatment device had a significant impact on removal. The microbial community structure of aquaculture wastewater was quite different before and after wastewater treatment. The abundance changes of Saccharimonadales and Mycobacterium affect the removal of sulfonamide ARGs.

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“…WWTPs-treated sewage has been discharged into surface water, and activated sludge in WWTPs has been reused as biological fertilizer, which has caused antimicrobials to enter the natural water cycle and to spread to soil [ 48 ]. Antimicrobials have been observed in wastewater, surface water, drinking water, groundwater, and soil to some extent [ 49 , 50 , 51 , 52 , 53 ], and the concentration is generally between ng/L and mg/L levels [ 54 ].…”

Section: The Usage and Fate Of Antimicrobials In The Environmentmentioning

confidence: 99%

“…The factors affecting antimicrobial resistance spread have been reported in many studies, and are similar to the factors affecting antimicrobial contamination mentioned above ( Figure 2 ). It has been reported that residual antimicrobials are the major factor inducing bacteria to accept environmental ARGs and increase the mutation rate of bacteria [ 21 , 51 ]. In addition to antimicrobials, heavy metals also play an important role in the development and spread of antimicrobial resistance.…”

Section: The Fate Of Antimicrobial Resistance In the Environmentmentioning

confidence: 99%

Antimicrobial and the Resistances in the Environment: Ecological and Health Risks, Influencing Factors, and Mitigation Strategies

Wang

Weng

Luo

et al. 2023

Toxics

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Antimicrobial contamination and antimicrobial resistance have become global environmental and health problems. A large number of antimicrobials are used in medical and animal husbandry, leading to the continuous release of residual antimicrobials into the environment. It not only causes ecological harm, but also promotes the occurrence and spread of antimicrobial resistance. The role of environmental factors in antimicrobial contamination and the spread of antimicrobial resistance is often overlooked. There are a large number of antimicrobial-resistant bacteria and antimicrobial resistance genes in human beings, which increases the likelihood that pathogenic bacteria acquire resistance, and also adds opportunities for human contact with antimicrobial-resistant pathogens. In this paper, we review the fate of antimicrobials and antimicrobial resistance in the environment, including the occurrence, spread, and impact on ecological and human health. More importantly, this review emphasizes a number of environmental factors that can exacerbate antimicrobial contamination and the spread of antimicrobial resistance. In the future, the timely removal of antimicrobials and antimicrobial resistance genes in the environment will be more effective in alleviating antimicrobial contamination and antimicrobial resistance.

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Fate of antibiotics and antibiotic resistance genes in home water purification systems

Cited by 45 publications

References 37 publications

Detection Enhancement of One Multifunctional Cd-Metal–Organic Framework toward Tetracycline Antibiotics by Simply Mixing Eu³⁺ in Suspension

Detection Enhancement of One Multifunctional Cd-Metal–Organic Framework toward Tetracycline Antibiotics by Simply Mixing Eu³⁺ in Suspension

Removal of Sulfonamide Resistance Genes in Fishery Reclamation Mining Subsidence Area by Zeolite

Antimicrobial and the Resistances in the Environment: Ecological and Health Risks, Influencing Factors, and Mitigation Strategies

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Fate of antibiotics and antibiotic resistance genes in home water purification systems

Cited by 45 publications

References 37 publications

Detection Enhancement of One Multifunctional Cd-Metal–Organic Framework toward Tetracycline Antibiotics by Simply Mixing Eu3+ in Suspension

Detection Enhancement of One Multifunctional Cd-Metal–Organic Framework toward Tetracycline Antibiotics by Simply Mixing Eu3+ in Suspension

Removal of Sulfonamide Resistance Genes in Fishery Reclamation Mining Subsidence Area by Zeolite

Antimicrobial and the Resistances in the Environment: Ecological and Health Risks, Influencing Factors, and Mitigation Strategies

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Product

Resources

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Detection Enhancement of One Multifunctional Cd-Metal–Organic Framework toward Tetracycline Antibiotics by Simply Mixing Eu³⁺ in Suspension

Detection Enhancement of One Multifunctional Cd-Metal–Organic Framework toward Tetracycline Antibiotics by Simply Mixing Eu³⁺ in Suspension