Fatality from acute chlorfenapyr poisoning

Toxicity from Intra-Abdominal Injection of Chlorfenapyr

“…Chlorfenapyr is not a well-studied chemical; however, some studies have shown that the symptoms of chlorfenapyr toxicity include fever, diaphoresis, general fatigue, blurred vision, psychological effects, and rhabdomyolysis [2, 3]. We did not detect fever, nausea, vomiting, or psychological effects in our patient, but we did observe severe diaphoresis.…”

“…In 2007, a case was reported in Japan in which a farmer who had inhaled chlorfenapyr vapors showed severe fatigue and died 7 days after exposure [2]. And in Korea, a 55-year-old man ingested chlorfenapyr and died after 7 days [3]. Here, we describe a case of a 74-year-old man who injected chlorfenapyr into his intra-abdominal space with suicidal intent.…”

A patient fatality following the ingestion of a small amount of chlorfenapyr

“…[2456] Tharaknath et al ., reported that a similar fatality presented delayed adverse neurological effects ten days after chlorfenapyr ingestion and Kwon et al ., reported symptoms approximately 2 weeks after chlorfenapyr ingestion. [56] In both cases, the patients presented brain and spinal cord magnetic resonance imaging (MRIs) demonstrating the demyelination of the CNS.…”

“…Three fatal chlorfenapyr poisoning cases were recently reported in South Korea and India. [456] In addition to toxicity from oral ingestion, there was one case of death from chlorfenapyr vapor exposure. [3] Because of these findings, we believe that chlorfenapyr is highly toxic to humans, and the use of chlorfenapyr may need to be restricted in the same way that paraquat is controlled.…”

“…Some fatal cases of chlorfenapyr poisoning by oral ingestion have been reported in the medical literature. [23456] However, fatality case from small amount of chlorfenapyr ingestion has not been reported. Here, we present a fatal case caused by delayed chlorfenapyr toxicity, even though only a small amount was ingested.…”