Fatal Tuberculosis in a General Hospital a Diagnostic Problem

Treip, C. S.; Meyers, David G.

doi:10.1016/s0140-6736(59)90366-6

Cited by 28 publications

(12 citation statements)

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“…Often in the elderly, chronic illnesses, such as this patient's chronic bronchitis and longstanding cough, mask the symptoms of tuberculosis. A fre quently cited reason for delays in the diagno sis of tuberculosis, especially in the elderly, is the presence of such atypical radiographic patterns as solitary nodules, mass-like densi ties, extensive bronchopneumonia, and lower lobe infiltrates [12,20,23,35]. This patient's lingular infiltrate was initially thought to rep resent a neoplasm.…”

Section: Pulmonary Tuberculosismentioning

confidence: 97%

“…This patient did not have the classic symptoms of pulmonary tuberculosis: a new cough, fever, and weight loss. A paucity of respiratory symptoms is frequently observed among the elderly [35]. The lingular infiltrate on his chest radiograph was an incidental finding during the evaluation of an unrelated medical problem.…”

Section: Pulmonary Tuberculosismentioning

confidence: 99%

“…Patients over the age of 60 make up the majority of both undiagnosed and fatal cases of miliary tuberculosis [6,10,28,35]. The lower frequency of accompanying cavitary pulmonary tuberculosis and the presence of concomitant diseases may account for the frequent failure to diagnose miliary tubercu losis antemortem in the elderly.…”

Section: Miliary Tuberculosismentioning

confidence: 99%

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Aging and Tuberculosis

Nagami¹,

Yoshikawa²

1984

Gerontology

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In the United States, an increasing proportion of all forms of reactivation tuberculosis occurs in patients over the age of 60 years. Atypical presentations and presence of chronic illness obscure the diagnosis of tuberculosis in the elderly. Prompt diagnosis requires a high index of suspicion and aggressive procedures for diagnostic microbiology. Short-course (9 months) chemotherapy with isoniazid and rifampin is the treatment of choice for elderly patients with uncomplicated pulmonary tuberculosis. Isoniazid chemoprophylaxis is recommended for selected elderly patients.

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Section: Pulmonary Tuberculosismentioning

confidence: 97%

Section: Pulmonary Tuberculosismentioning

confidence: 99%

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Aging and Tuberculosis

Nagami¹,

Yoshikawa²

1984

Gerontology

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“…A history of TB is present in only 10% to 20% of patients. [1][2][3][4][5][6][7][8][9][10][11][12][13] The chest x-ray (CXR) is often the first diagnostic test in which miliary TB may be suspected. The sensitivity of the CXR for miliary TB is approximately 60% to 70%.…”

mentioning

confidence: 99%

“…Miliary TB may be accompanied by generalized adenopathy, hepatomegaly, splenomegaly, or basilar meningitis (Table 1). [1][2][3][4][5][6][7][8][9][10][11][12][13][18][19][20] Nonspecific laboratory findings of miliary TB are variable and include leukopenia, relative leukopenia, monocytosis, anemia, thrombocytosis, an elevated erythrocyte sedimentation rate (usually Յ70 mm/h), and normal serum ferritin levels. 1,6,9,13,20 …”

mentioning

confidence: 99%