Fatal Systemic Herpes Simplex Virus Type 2 Infection in a Healthy Young Woman

Whorton, C. Merrill; Thomas, Diane; Denham, Susan

doi:10.1097/00007611-198301000-00021

Cited by 22 publications

(2 citation statements)

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“…Single organ involvement, most commonly in the gastrointestinal tract, is usualIy a result of recurrent infections.l\Iulti-pIe organ involvement may occur in the setting of hematogenous dissemination, which occurs via infection of circulating leukocytes. Occasionally, it is seen in pregnant women, typi-calIy in the second or third trimester [5][6][7][8]141. Hepatitis is the most commonly reported organ involved in disseminated HSV (visceral infection), but there are other manifestations of visceral involvement that may be overlooked unless HSV is suspected (Fig 2).…”

Section: Visceral Infectionsmentioning

confidence: 99%

Herpes SimplexInfections in the Critical Care Setting

Knobil

Wiener

Zenilman

1997

J Intensive Care Med

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Knobil K, \Viener C, Zenilm:m J. Herpes simplex infections in the critical care selling. J Intensive Care Med 1997;12:93--103.Infcctions caused by herpes simplex virus (lISV) l}'pes 1 and 2 are widely prevalent and usually asymptomatic. In the immunocompromised or severely ill patient, however, lISV can cause a \'ariel}' of mucosal and systemic syndromes. Organ systems most susceptible include the gastrointestinal tract,lungs, and the central neo'ous system. Systemic dissem· inated disease may also occur. With the exception of herpes encephalitis, clinical diagnosis of serious IISV infections is difficult, because it occurs in hosts who are susceptible to a wide range of infectious and metabolic problems. "'e review the presenting syndromes of IISV infection in the critically ill patient, and outline current concepts for diagnosis and treatment.From the°Dh'ision of Pulmonary and Critical Care Medicine, and the tDh'ision

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Section: Visceral Infectionsmentioning

confidence: 99%

Herpes SimplexInfections in the Critical Care Setting

Knobil

Wiener

Zenilman

1997

J Intensive Care Med

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“…Such patients are usually immunocompromised (see p. 80); however, cases have been described in otherwise apparently normal individuals (Whorton et al 1983), and in association with pregnancy where primary HSV has disseminated and resulted in the death of both mother and foetus (Peacock and Sarubbi 1983). Organs that may be involved include the liver, lungs, oesophagus, adrenals, pancreas, the small and large bowel, the kidneys and the bone marrow .…”

Section: Visceral Infectionsmentioning

confidence: 99%

Herpes Simplex Virus

Mindel¹

1989

The Bloomsbury Series in Clinical Science

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Fulminant Hepatic Failure due to Genital Herpes in a Healthy Woman: Was the Case a First?

Whorton¹

1985

JAMA

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issue of JAMA, a question regarding management of Frey's syndrome was posed.1 Additional means for treatment of the symptomatic patient include topical scopolamine cream (0.1%), commercial antiperspirants, and tympanic neurectomy.2 Antiperspirants are of only occasional value, and scopolamine cream usually affords but temporary relief because the sweat glands become refractory. Tympanic neurectomy is indicated when the gustatory sweating is severe enough to embarrass the patient.Tympanic neurectomy involves elevation of the tympanic membrane (eardrum), in order to expose the mucosa of the middle ear. Along the medial surface of the middle ear are found the autonomic secretomotor nerve fibers that normally regulate salivary secretion of the parotid gland and are responsible for gustatory sweating following parotidectomy. These fibers are disrupted, and the tympanic membrane is returned to its original position. Abolition of symptoms is usually immediate and complete following surgery. Complications are uncommon in skilled hands.

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Fatal Systemic Herpes Simplex Virus Type 2 Infection in a Healthy Young Woman

Cited by 22 publications

References 0 publications

Herpes SimplexInfections in the Critical Care Setting

Herpes SimplexInfections in the Critical Care Setting

Herpes Simplex Virus

Fulminant Hepatic Failure due to Genital Herpes in a Healthy Woman: Was the Case a First?

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