Fatal superinfection with Monilia in gynecological surgery

Fox, Leon Parrish

doi:10.1016/0002-9378(71)90622-3

Cited by 6 publications

(3 citation statements)

References 11 publications

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“…Many more have minor degrees of vaginal morbidity that may be causally associated with thrush fungi (Carroll, Stanley and Hurley, 1971 ;de Fonseka, 1972). More serious infections caused by C. albicans and other pathogenic species of Candida occur in obstetric and gynaecological practice, and five fatal cases of systemic candidosis were described by Fox (1971), who reviewed 11 other cases.…”

Section: I S T R I B U T I O N a N D S I G N I F I C A N C E O F C mentioning

confidence: 99%

Distribution And Significance Of Candida Precipitins In Sera From Pregnant Women

Stanley¹,

Hurley²,

Carroll³

1972

Journal of Medical Microbiology

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MATERIALS AND METHODS Preparation of antigensThree antigens derived from a strain of Candida albicans, group A (London School of Hygiene and Tropical Medicine no. 3153), were produced in bulk to minimise batch variation and stored in the freeze-dried state.(a) Mickle-disintegrated cytoplasmic antigen. A modification of the methods of Stallybrass (1964) and Taschdjian et al. (1964a) was used. The fungus was grown in shaken culture at 37°C for 48 hr. The culture medium was modified Sabouraud's glucose broth (peptone

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Section: I S T R I B U T I O N a N D S I G N I F I C A N C E O F C mentioning

confidence: 99%

Distribution And Significance Of Candida Precipitins In Sera From Pregnant Women

Stanley¹,

Hurley²,

Carroll³

1972

Journal of Medical Microbiology

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“…[1][2][3][4][5][6][7][8][9][10][11][12] The major risks arising from the tumor itself are 1) preexisting subclinical infections in proliferating and necrotic malignancy and 2) possible immunosuppressive effects exerted by the tumor itself. [13][14][15][16][17][18][19][20][21][22][23] In addition to the usual risks deriving from host factors, from surgical procedures, and from the tumor itself, invasive diagnostic techniques used before surgery add to the risk from the possibility of preexisting occult infection of the genital tissue and possible introduction of nosocomial infection. Invasive procedures such as cystoscopy, proctoscopy, needle biopsy, and dilatation and curettage are routine in the work-up of a patient with gynecologic malignancy.…”

mentioning

confidence: 99%

Infectious Morbidity After Radical Vulvectomy

Elg

Carson

Brooker

et al. 1994

Infectious Diseases in Obstetrics and Gynecology

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Objective: This retrospective investigation describes the infectious morbidity of patients following radical vulvectomy with or without inguinal lymph node dissection. Methods: The charts of patients undergoing radical vulvectomy between January 1, 1986, and September 1, 1989, were reviewed for age, weight, cancer type, tumor stage, operative procedure(s), prophylactic antibiotic and its length of use, febrile morbidity, infection site, culture results, significant medical history, and length of use and number of drains or catheters used. Results: The study group was composed of 61 patients, 14 of whom underwent a radical vulvectomy and 47 who also had inguinal lymph node dissection performed. Twenty-nine patients (48%) had at least 1 postoperative infection. Five patients (8%) had 2 or more postoperative infections. The site and incidence of the infections were as follows: urinary tract 23%, wound 23%, lymphocyst 3%, lymphatics (lymphangitis) 5%, and bowel (pseudomembranous colitis) 3%. The most common pathogens isolated from both urine and wound sites were Pseudomonas aeruginosa, enterococcus, and Escherichia coli. A significant decrease in wound infection was demonstrated when separate incisions were made for inguinal lymph node dissection (P <0.05). The mean number of days to onset of postoperative infection for wound, urine, lymphatics, lymphocyst, and bowel were 11, 8, 57, 48, and 5, respectively. Conclusions: We conclude that the clinical appearance of post-radical vulvectomy infections is delayed when compared with other post-surgical wound infections. Second, utilizing separate inguinal surgical incisions may reduce infectious morbidity. Finally, tumor stage and type do not necessarily increase the infectious morbidity of radical vulvar surgery.

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“…Septicemia during pregnancy not only represents a teratogenic risk but also entails the danger of abortion. Candida septicemia in pregnancy has been reported as a cause of septic or missed abortion [23,24], and intraamniotic infection with C. albicans may lead to the rupture of membranes and thus to premature and stillbirth or even abortion [16]. In addition, untreated systemic candidiasis may lead to deep organ involvement such as liver, spleen and brain abscesses and, as demonstrated in our case, endophthalmitis.…”

Section: Literature Review and Discussionmentioning

confidence: 80%

Fluconazole inCandida albicans sepsis during pregnancy: Case report and review of the literature

Wiesinger¹,

Wenisch²,

Breyer³

et al. 1996

Infection

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Candida sepsis during pregnancy is a rare but life-threatening complication of infection with Candida albicans. In contrast to the situation with other antimicrobial agents, there exists only limited experience with systemic antifungal therapy during pregnancy. A recent report focuses on amphotericin B treatment in systemic fungal infection during pregnancy. The present report discusses a pregnant patient with Candida albicans sepsis and endophthalmitis as well as candida infection of the oral and genital mucous membranes, after hyperalimentation and broad spectrum antibiotic therapy via a central venous catheter. The patient was treated with 10 mg/kg fluconazole from week 16 of gestation for a total duration of 50 days. Adverse effects did not occur and the rest of the pregnancy proceeded favourably for both the mother and the baby.

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Fatal superinfection with Monilia in gynecological surgery

Cited by 6 publications

References 11 publications

Distribution And Significance Of Candida Precipitins In Sera From Pregnant Women

Distribution And Significance Of Candida Precipitins In Sera From Pregnant Women

Infectious Morbidity After Radical Vulvectomy

Fluconazole inCandida albicans sepsis during pregnancy: Case report and review of the literature

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