Fatal outcome of posterior reversible encephalopathy syndrome (PRES) in a lupus nephropathy patient: A case report

Afilal, Ihssane; Nasri, Siham; Bendaoud, Mustapha; Mahjouba, Hajar; Guerrouj, Imane; Aidid, Fathia; Abbou, Widad; Aichouni, Narjisse; Kamaoui, Imane; Skiker, Imane

doi:10.1016/j.radcr.2022.03.084

Cited by 1 publication

(2 citation statements)

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“…SLE predominantly affects women during their reproductive years, occurring in about 1/1000 women aged between 15 and 45 years [1]. Pregnancy and the postpartum period provoke an exacerbation of SLE [3], which requires aggressive cytostatic therapy that can cause life-threatening conditions for the fetus and complications for the mother [4], one of which is PRES [5], phased diagnosis, and timely treatment.…”

Section: Anmentioning

confidence: 99%

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Case of successful treatment of acute respiratory distress syndrome in the parturient woman with systemic lupus erythematosus and cerebral cyst of the third ventricular complicated by posterior reversible encephalopathy syndrome

Bykova,

Kasherininov,

Bautin

et al. 2023

JIMH

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Pregnancy and the postpartum period provoke an exacerbation of systemic lupus erythematosus (SLE), which requires aggressive cytostatic therapy that can cause life-threatening conditions for the fetus and complications for the mother, one of which is posterior reversible encephalopathy syndrome (PRES- syndrome). The article describes a clinical case of successful treatment of acute respiratory distress syndrome (ARDS) in a 22-year-old woman in labor with high activity of SLE during pregnancy complicated by the development of PRES syndrome. Also, for the first time in the postpartum period, the patient was diagnosed with occlusive periventricular hydrocephalus, a giant cyst of the third ventricle. An emergency endoscopic cyst ventriculocisternostomy was performed. In the future, the development of severe ARDS against the background of sepsis, which required the setting of extracorporeal membrane oxygenation (ECMO). A multidisciplinary approach and timely therapy saved the life of a young mother.

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Section: Anmentioning

confidence: 99%

“…The pathophysiology of PRES in SLED is not yet completely explained [3]. However, there is theory of the reflex hypopefusion of the brain secondary to endothelial dysfunction and exacerbated by vasoconstriction, spasm and/or autoimmune activation, therefore resulting in vascular hyperpermeability and vasogenic edema [4].…”

Section: Anmentioning

confidence: 99%