Fatal Hemoptysis in a Patient With Left Mainstem Bronchus Squamous Cell Carcinoma Treated With Photodynamic Therapy

MacRosty, Christina R.; Burks, Allen Cole; Ghosh, Shobha; Akulian, Jason; Belanger, Adam R.

doi:10.1097/lbr.0000000000000611

Cited by 2 publications

(2 citation statements)

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“…If the lesion location is adjacent to the large blood vessels surrounding the airway, the risk of massive hemoptysis should be considered prior to administering therapy [29]. This is also true for large central airway tumors that may have large vascular beds [29,30]. As necrosis occurs, these perforating vessels can potentially lead to significant bleeding.…”

Section: Approach To Photodynamic Therapy In Lung Cancermentioning

confidence: 99%

“…Depending upon the shape and course of the lesions, consideration should be given to the anticipated inflammatory effects during photodynamic therapy as the process of controlled and uncontrolled cell death occurs. The areas particularly at risk are the trachea, carina, and main stem bronchi [17,29]. In these cases, long or circumferential tumors would be at a higher risk of obstructing the airway given the expansion associated with edema that would be anticipated with photodynamic therapy [17].…”

Section: Approach To Photodynamic Therapy In Lung Cancermentioning

confidence: 99%

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Clinical Usage of Photodynamic Therapy

Patel¹,

Musani²

2021

Photodynamic Therapy - From Basic Science to Clinical Research

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This chapter will provide a brief overview of the fundamentals of photodynamic therapy with an emphasis on its use in a clinical setting. Beginning with the history and fundamental science underlying photodynamic therapy and delving into clinical uses. There will be a primary focus on understanding the use of photodynamic therapy under currently approved clinical indications along with their limitations. There are a number of approved therapeutic indications for photodynamic therapy, but there are important limitations and contraindications when applying this therapy. Photodynamic therapy, as applied to the clinical treatment of cancer will be the primary focus with further emphasis on endoluminal and specifically endobronchial cancer as the primary case study.

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Section: Approach To Photodynamic Therapy In Lung Cancermentioning

confidence: 99%

Section: Approach To Photodynamic Therapy In Lung Cancermentioning

confidence: 99%