Fatal hemoptysis and high dose-rate endobronchial brachytherapy: is there any relationship with clinical or technical parameters

Irradiated volume and the risk of fatal hemoptysis in patients submitted to high dose-rate endobronchial brachytherapy

“…In our preliminary report with 67 patients [32], left bronchial lesions presented a marginal significance (p = 0.06) as a risk factor for FH, not confirmed in this study (p = 0.36, Table 1). When the lesions were classified in central or peripheral locations, this was also not a significant predictive factor for FH, even with a supposed higher risk for patients with lesions in close relationship with major vessels.…”

“…In our initial experience already cited above [32], the irradiated volume at prescribed dose (V100) was a risk factor for FH. An arbitrary value of 30 cm 3 for V100 was assumed as the cut-off for FH, a value between the mean values of V100 obtained for the high risk (37.4 cm 3 ) versus the low risk (24.9 cm 3 ) patients.…”